Results 71 to 80 of about 3,887,366 (252)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

"Variación sintáctica en las construcciones pasivas: las preposiciones introductoras del agente" [PDF]

open access: yes, 2015
El presente trabajo constituye un estudio diacrónico acerca de la pérdida de la preposición de como introductora del complemento agente y la subsiguiente propagación de la preposición por en construcciones pasivas perifrásticas con ser.
Nieuwenhuijsen, Dorien, ILS Variation
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Nicotine in Fine Particles in Shanghai: Temporal Variations and Influencing Factors

open access: yesAtmosphere
To investigate the temporal and spatial variations in smoking activities in Shanghai, atmospheric fine particles (aerodynamic diameter ≤ 2.5 μm) were collected at four sites in different functional zones, a central urban site (XJH), an urban site (PD), a
Jialiang Feng   +5 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Year-to-Year Variability of Indoor Radon Concentrations in Finnish Homes

open access: yesAtmosphere
Background: Health risks from radon exposure depend on long-term radon concentrations. This study quantified interannual variability in residential radon concentrations in Finland and evaluated its implications for exposure assessment and measurement ...
Tuukka Turtiainen   +5 more
doaj   +1 more source

Connecting Resource Tracking by Frugivores to Temporal Variation in Seed Dispersal Networks

open access: yesFrontiers in Ecology and Evolution, 2017
Mutualistic interactions between species are crucial for the maintenance and functioning of the community. Current research has shown the importance of not only understanding the structure of these mutualistic interaction networks but also their temporal
Jason M. Gleditsch   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Suppression of period doubling chetter in high-speed milling by spindle speed variation [PDF]

open access: yes, 2011
Spindle speed variation is a well known technique to suppress regenerative machine tool vibra- tions, but it is usually considered to be effective only for low spindle speeds.
Arnaud, Lionel   +9 more
core   +1 more source

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