Results 221 to 230 of about 273,018 (289)

Targeted Degradation of Picornaviral 3C Protease via PROTACs Confers High Barrier to Viral Resistance and Broad‐Spectrum Antiviral Activity

Advanced Science, EarlyView.
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng, Junyu Chen, Yingyue Pang, Yuanyuan Zhang, Siqian Chen, Guoliang You, Xiaoman Tian, Zhongxin Xu, Jing Wang, Luqing Shang   +9 more
wiley   +1 more source

Remote Work Opportunities and Preferences Among Public Health Employees: Implications for Job Satisfaction, Burnout, and Retention. [PDF]

J Public Health Manag Pract
Gee M, Yeager VA.
europepmc   +1 more source

Not who we treat, but how we treat: Emphasizing treatment adherence in neuromodulation outcomes. [PDF]

Interv Pain Med
D'Souza RS, Hao D, Hayek SM.
europepmc   +1 more source

The Impact of Online Labor Platforms on Workforce Management in Health Care. [PDF]

Interact J Med Res
Ahmadi Shad M, Simon M, Liberatore F.
europepmc   +1 more source

No Slack in the System: Workforce Strain, Redistribution, and Recalibration in State and Local Government Public Health. [PDF]

J Public Health Manag Pract
Robins M, Leider JP, Leider JP, McCullough JM, Hare Bork R, Castrucci BC.   +5 more
europepmc   +1 more source

From crisis response to country control: Restoring agency and sustainability in global health. [PDF]

PLoS Med
Okereke E.
europepmc   +1 more source

From Care to Justice: Reframing Nursing Education Through Relational Ethics and Epistemic Inclusion. [PDF]

Nurs Philos
Assem-Erhaze EK.
europepmc   +1 more source