Results 51 to 60 of about 273,018 (289)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Intervention mapping for development of a participatory return-to-work intervention for temporary agency workers and unemployed workers sick-listed due to musculoskeletal disorders

BMC Public Health, 2009
Background In the past decade in activities aiming at return-to-work (RTW), there has been a growing awareness to change the focus from sickness and work disability to recovery and work ability. To date, this process in occupational health care (OHC) has
Schellart Antonius JM, Anema Johannes R, Vermeulen Sylvia J, van Mechelen Willem, van der Beek Allard J   +4 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Temporary Agency Work in Europe

, 2006
Chapter 9 by Michon provides an overview of nonstandard work in Europe and discusses one institutional response—the growth of tem-18 Gleasonporary help fi rms (also called temporary work agencies [TWAs]). As the need for more fl exible labor markets has become evident, temporary work agencies have emerged as institutions that facilitate fl exibility ...
openaire   +4 more sources

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Blue-collar temporary agency workers’ social interactions and relations, workplace social support and occupational well-being in different work arrangements: a qualitative study of the Swedish manufacturing industry

Cogent Psychology
Temporary agency work is growing in European countries. Blue-collar temporary agency workers (BC-TAWs) in the manufacturing industry are described as subject to unfavourable work conditions and low occupational well-being.
Andreas Kjörling, Tuukka Kaidesoja, Eva L. Bergsten   +2 more
doaj   +1 more source

conference interpreters in Japan: Exploring status through the sociology of work and of professions

Interpreting and Society, 2022
This article investigates the professional status of conference interpreters in Japan, by focusing on interpreters employed as haken , that is, dispatched temporary workers. Combining the perspectives of interpreting studies and the sociology of work, it
Deborah Giustini
doaj   +1 more source

Trajectories of precarious employment and the risk of myocardial infarction and stroke among middle-aged workers in Sweden: A register-based cohort study

The Lancet Regional Health. Europe, 2022
Summary: Background: The aim is to identify trajectories of precarious employment (PE) over time in Sweden to examine associations of these with the subsequent risk of myocardial infarction (MI) and stroke.
Nuria Matilla-Santander, Carles Muntaner, Bertina Kreshpaj, Virginia Gunn, Johanna Jonsson, Lauri Kokkinen, Jenny Selander, Sherry L Baron, Cecilia Orellana, Per-Olof Östergren, Tomas Hemmingsson, David H. Wegman, Theo Bodin   +12 more
doaj   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source