Results 31 to 40 of about 114,384 (301)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

The Impact of Megaproject Stakeholders’ Psychological Ownership on Cooperative Innovation Performance: Territorial Behavior and Social Loafing as Mediator

open access: yesAdvances in Civil Engineering, 2022
Megaprojects encounter numerous innovation challenges as well as cross-organization cooperation demands. The paper aims to clarify the relationship between stakeholders’ psychological ownership and cooperative innovation performance.
Zhen Chen
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Problems of Evaluation of Temporary Employment’s Influence on Injuries and Occupational Diseases

open access: yesСоціальна економіка, 2018
In the article special attention is paid to the problems of estimating the effect of temporary employment on injuries and occupational diseases. The purpose of the research is to form theoretical and methodological basis for assessing the impact of ...
Yuliya Lazebnyk
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Organizing in the shadow of donors: How donations market regulates the governance practices of sponsored projects in non-governmental organizations

open access: yesBAR: Brazilian Administration Review, 2019
The purpose of this study is to analyze the influence of donors in the organization of governance practices of sponsored projects in non-governmental organizations (NGOs) from an agency theory perspective.
Adonai José Lacruz   +2 more
doaj   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur   +5 more
wiley   +1 more source

Work organizational outcomes of the use of temporary agency workers

open access: yes, 2012
This article examines work organizational dynamics in workplaces using temporary agency workers. Previous research has principally either emphasized one effect, the division into core and periphery, or criticized this effect.
Håkansson, Kristina,   +1 more
core   +1 more source

Management and Organization of Temporary Agency Work Foreword

open access: yes, 2014
Over the past two decades, the concept of “regular employment” has been challenged and changed rapidly and fundamentally. We have seen a growth of short-term employment.
Koene, Bas   +2 more
core   +1 more source

Practopoietic Lens to Conceptualize Temporary Organizing

open access: yesSingaporean Journal of Business Economics and Management Studies, 2018
The purpose of this paper is to conceptualize temporary organizing as a practopoietic system. We critically review the current conceptualizations of projects; from the traditional project management perspective, and the temporary organization perspective using a systems approach. By juxtaposing the characteristics of the project with a system, we argue
Dwivedula, Ravikiran   +2 more
openaire   +2 more sources

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