Results 41 to 50 of about 62,717 (282)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The application of post tender negotiation procedure: a public sector procurement perspective in UK
International Journal of Information Systems and Project Management, 2016 0
Peter Manso, Athanasios Nikas, , ,
doaj +1 more source
The impact of procurement method on costs of procurement [PDF]
, 2005 Collaborative working methods offer the hope of reduced waste, lower tendering costs and improved outputs. The costs of tendering may be influenced by the introduction of different working methods.
Greenwood, D. +2 more
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Jurnal Pembaharuan Hukum, 2018 The resolutions of non-performing loans with tendering guarantee Encumbrance Often bring up the resistance of the debtor in the form of Civil Lawsuit filed to the District Court the which is due to the complexity of the auction and Several weaknesses ...
Lusia Sulastri
doaj +1 more source
Results in Engineering, 2022 Construction industry is dynamic in nature worldwide because of growing ambiguities in costs, techniques, and construction processes. The construction projects undergo various events and activities with change of stakeholders in constantly variable ...
Muhammad Saleem Raza +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Public Sector Contracting Model for Management of Construction Tender Price Volatility
Journal of Construction Project Management and Innovation, 2023 Construction tender price volatility threatens desirable infrastructure push in the public sector. The damaging effects of escalating tender prices outweigh the socioeconomic benefits of such infrastructure.
moffat tembo +2 more
doaj +1 more source
The fee tendering and service quality issue revisited [PDF]
, 2007 Purpose - It is a little over twenty years since mandatory fee scales were abolished by UK professional bodies. During this period fee levels have fluctuated with economic demand, and new procurement strategies such as partnering have been developed, but
Hoxley, M
core +1 more source