Results 31 to 40 of about 25,727 (257)

Global Responses of Il-1β-Primed 3D Tendon Constructs to Treatment with Pulsed Electromagnetic Fields

Cells, 2019
Tendinopathy is accompanied by a cascade of inflammatory events promoting tendon degeneration. Among various cytokines, interleukin-1β plays a central role in driving catabolic processes, ultimately resulting in the activation of matrix ...
Renate Gehwolf, Bettina Schwemberger, Malik Jessen, Stefanie Korntner, Andrea Wagner, Christine Lehner, Nadja Weissenbacher, Herbert Tempfer, Andreas Traweger   +8 more
doaj   +1 more source

Bioreactor Design for Tendon/Ligament Engineering [PDF]

Tissue Engineering Part B: Reviews, 2012
Tendon and ligament injury is a worldwide health problem, but the treatment options remain limited. Tendon and ligament engineering might provide an alternative tissue source for the surgical replacement of injured tendon. A bioreactor provides a controllable environment enabling the systematic study of specific biological ...
Wang, T., Gardiner, B.S., Lin, Z., Rubenson, J., Kirk, T.B., Wang, A., Xu, J., Smith, D.W., Lloyd, D.G., Zheng, M.H.   +9 more
openaire   +4 more sources

Clinical perspectives for repairing rotator cuff injuries with multi-tissue regenerative approaches

Journal of Orthopaedic Translation, 2022
Background: In the musculoskeletal system, bone, tendon, and muscle form highly integrated multi-tissue units such as the rotator cuff complex, which facilitates functional and dynamic movement of the shoulder joint. Understanding the intricate interplay
Xu Zhang, Dan Wang, Zuyong Wang, Samuel Ka-kin Ling, Patrick Shu-hang Yung, Rocky S. Tuan, Dai Fei Elmer Ker   +6 more
doaj   +1 more source

Biomarkers for tissue engineering of the tendon-bone interface. [PDF]

PLoS ONE, 2018
The tendon-bone interface (enthesis) is a highly sophisticated biomaterial junction that allows stress transfer between mechanically dissimilar materials.
Lara A Kuntz, Leone Rossetti, Elena Kunold, Andreas Schmitt, Ruediger von Eisenhart-Rothe, Andreas R Bausch, Rainer H Burgkart   +6 more
doaj   +1 more source

Biomimetic Scaffolds for Tendon Tissue Regeneration

Biomimetics, 2023
Tendon tissue connects muscle to bone and plays crucial roles in stress transfer. Tendon injury remains a significant clinical challenge due to its complicated biological structure and poor self-healing capacity.
Lvxing Huang, Le Chen, Hengyi Chen, Manju Wang, Letian Jin, Shenghai Zhou, Lexin Gao, Ruwei Li, Quan Li, Hanchang Wang, Can Zhang, Junjuan Wang   +11 more
doaj   +1 more source

Rebuilding Tendons: A Concise Review on the Potential of Dermal Fibroblasts

Cells, 2020
Tendons are vital to joint movement by connecting muscles to bones. Along with an increasing incidence of tendon injuries, tendon disorders can burden the quality of life of patients or the career of athletes.
Jin Chu, Ming Lu, Christian G. Pfeifer, Volker Alt, Denitsa Docheva   +4 more
doaj   +1 more source

New frontiers of tendon augmentation technology in tissue engineering and regenerative medicine: a concise literature review

Journal of International Medical Research, 2022
Tissue banking programs fail to meet the demand for human organs and tissues for transplantation into patients with congenital defects, injuries, chronic diseases, and end-stage organ failure.
Rangarirai Makuku, Jean-David Werthel, Leila Oryadi Zanjani, Mohammad Hossein Nabian, Marcarious M. Tantuoyir   +4 more
doaj   +1 more source

Engineering Multiscale Scaffold‐Free Mimetic Environments Within Microfibrous Scaffolds Enhances Tendon Regeneration

Small Structures
Promoting self‐organized regeneration, rather than nonfunctional repair, has emerged as a leading strategy for treating soft tissue injuries. Tissue self‐organization typically occurs in scaffold‐free environments; however, scaffolds can offer long‐range
Chiao‐Yu Tseng, Yen‐Ching Yang, Balchandar Navaneethan, Phuong Thi Thu Bui, Pei‐Syuan Lu, Chia‐Fu Chou, Po‐Ling Kuo, Chin‐Lin Guo   +7 more
doaj   +1 more source

Dexamethasone Is Not Sufficient to Facilitate Tenogenic Differentiation of Dermal Fibroblasts in a 3D Organoid Model

Biomedicines, 2023
Self-assembling three-dimensional organoids that do not rely on an exogenous scaffold but maintain their native cell-to-cell and cell-to-matrix interactions represent a promising model in the field of tendon tissue engineering.
Niklas Kroner-Weigl, Jin Chu, Maximilian Rudert, Volker Alt, Chisa Shukunami, Denitsa Docheva   +5 more
doaj   +1 more source

Generalized Dystonia With Cervical Predominance in a Patient With a De Novo TCF20 Variant

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT TCF20 has been implicated in developmental delay and intellectual disability, with dystonia reported less frequently. We describe a woman in her early twenties with childhood‐onset learning difficulties, progressive dysarthria, tremor, and generalized dystonia with marked cervical predominance, associated with a de novo TCF20 frameshift ...
Melisa Kilic, Petr Dusek, Ibrahim Kamaci, Bahar Gulmez, Gul Yalcin Cakmakli, Ersin Tan, Sibel Ugur Iseri, Zuhal Yapici   +7 more
wiley   +1 more source