Results 81 to 90 of about 25,727 (257)

Toward Mechanical Intelligence in Robotics

Advanced Robotics Research, EarlyView.
Robots can use their physical bodies to perform functions usually assigned to electronic sensors and controllers. This perspective defines mechanical intelligence through three core operations: filtering inputs, routing mechanical signals, and switching between states.
Xinyi Yang, Xinyi Ding, Tianyu Wang, Daniel I. Goldman, Shucong Li, Bolei Deng   +5 more
wiley   +1 more source

A Transnasal Endoscope for Robotically Assisted Gastroscopy

Advanced Robotics Research, EarlyView.
This work introduces a 4.25 mm diameter magnetically navigated transnasal endoscope for upper gastrointestinal (GI) screening and intervention. The system enables precise remote steering throughout the upper GI tract and is demonstrated through in vitro and in vivo experiments, including the robotic execution of preprogrammed retroflexions, trans ...
Alexandre Mesot, Michelle Mattille, Sean Lyttle, Shannon M. Chan, Philip W. Y. Chiu, Quentin Boehler, Bradley J. Nelson   +6 more
wiley   +1 more source

Artificial Single-Layer, Multi-Layer, and Gradient Scaffolds for Enhancing the Healing of Tendon-to-Bone Interfaces: A Mini-Review

Orthopedic Research and Reviews
Tianyi Song,1 Lin Guo,1 Changcheng Wang,2 Mingcheng Li3 1Second Department of Orthopedics, Affiliated Zhongshan Hospital, Dalian University, Dalian, Liaoning, 116001, People’s Republic of China; 2Department of Biomedical Engineering, School of Biomedical
Song T, Guo L, Wang C, Li M
doaj  

Shear‐Isolating Actuation System for Exosuit Using Movable Pulley With Webbing‐Driven Mechanism

Advanced Robotics Research, EarlyView.
Tendon‐driven exosuits can chafe the skin because the moving tendon slides against the wearer. A shear‐isolating actuation system combining a movable pulley with flat‐profile webbing keeps the body‐contacting tendon layer stationary, relocating relative motion away from the skin. The compact 145‐g actuator delivers 150 N of assistance, and benchtop and
Kyeongmin Lim, Gijoon Song, Jaewook Ryu, Sangeui Lee, Junyoung Moon, Giuk Lee   +5 more
wiley   +1 more source

Implications of Tissue Engineering for Tendon Repair and Regeneration

Journal of Functional Biomaterials
Tendon injuries affect millions of people globally and are among the most prevalent musculoskeletal conditions, frequently resulting in chronic pain, reduced mobility, and functional impairment.
Dana Ivanisova, Katarina Bevizova, Sara Vach Agocsova, Lubos Danisovic, Martina Culenova   +4 more
doaj   +1 more source

Advanced Flexible Robotic Systems for the Early Diagnosis and Treatment of Cancer and Cardiovascular Diseases

Advanced Robotics Research, EarlyView.
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong, Chi Cong Nguyen, Hannah Thuy Truong, Kefan Zhu, Adrienne Ji, James Davies, Emanuele Nicotra, Bibhu Sharma, Jingjing Wan, Patrick Pruscino, Shing Wai Wong, Hoang‐Phuong Phan, Phuoc Thien Phan, Nigel H. Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

Advanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu, Ruo‐xin Wang, Feng He, Qian Liu, Fu‐yin Li, Min Hui, Yu‐qian Shi, Yu Jiang, Qing‐hua Li, Jun‐wen Jing, Shi‐bin Yu, Li‐tian Ma, Qian‐nan Niu, Mian Zhang   +13 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Role of tendon-derived stem cells in tendon and ligament repair: focus on tissue engineer

Frontiers in Bioengineering and Biotechnology
This review offered a comprehensive analysis of tendon and ligament injuries, emphasizing the crucial role of tendon-derived stem cells (TDSCs) in tissue engineering as a potential solution for these challenging medical conditions.
Wei He, Chao Jiang, Ping Zhou, Xujun Hu, XiaoPeng Gu, XiaoPeng Gu, SongOu Zhang, SongOu Zhang, SongOu Zhang   +8 more
doaj   +1 more source