Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia +16 more
wiley +1 more source
Reactive oxygen species in tendon injury and repair. [PDF]
Kračun D +3 more
europepmc +1 more source
Early synovial regulatory T cell engagement in posttraumatic osteoarthritis
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early post‐injury biological processes within the synovium shape disease trajectories. We investigated whether synovial regulatory T (Treg) cells are engaged during the early phase following joint injury and whether experimental enrichment ...
Xueyou Zhang +5 more
wiley +1 more source
The treatment of acute tendon injury with small extracellular vesicles originating from TNFAIP6<sup>-</sup> ADSCs subpopoulation both in vitro and in vivo. [PDF]
Liu H +13 more
europepmc +1 more source
The dead still teach the living: Body donor dissection in the digital age of anatomy education
Abstract Donor‐based dissection has become increasingly contested in modern medical curricula as digital anatomy platforms, simulation technologies, virtual dissection tables, three‐dimensional reconstructions, and artificial intelligence‐supported learning have expanded.
Uğur Baran Kasırga
wiley +1 more source
Therapeutic Effects of Polydeoxyribonucleotide and Atelocollagen into Achilles Tendon Injury in a Rat Model. [PDF]
Kim DS +5 more
europepmc +1 more source
Guidelines for designing and implementing game‐based learning in comparative anatomy education
Abstract Game‐based learning (GBL) is increasingly used in health professions anatomy education to promote engagement, knowledge acquisition, collaboration, and application of knowledge. However, its application to comparative veterinary anatomy remains fragmented, with limited guidance on how games can be systematically designed around the specific ...
Arthur Chin Haeng Lau +1 more
wiley +1 more source
ROS-responsive hydrogel loaded with capsaicin promotes tenogenic differentiation of tendon stem/progenitor cells and enhances tendon injury repair. [PDF]
Zhu YL +8 more
europepmc +1 more source
Accurate Measurement in All‐inside Posterior Cruciate Ligament Reconstruction: A Technical Note
Abstract With the increasing rate of posterior cruciate ligament reconstruction (PCLr) and growing adoption of the all‐inside PCLr, the existing literature lacks an optimal surgical protocol for this technique. It is well recognized that variations in knee size and intraoperative positioning pose challenges in determining the key parameter—the length ...
Daoliang Xu +4 more
wiley +1 more source
NSUN2-engineered human umbilical cord mesenchymal stem cell-derived exosomes ameliorate tendon injury by promoting DNM2 expression. [PDF]
Liu Y +7 more
europepmc +1 more source

