Results 1 to 10 of about 316 (103)

Impurity profiling method development and validation of metformin hydrochloride and teneligliptin hydrobromide hydrate in their combination tablet dosage form by using RP-HPLC with UV/PDA detector [PDF]

Future Journal of Pharmaceutical Sciences, 2021
Background An accurate, precise and robust analytical method was developed for the impurity profiling in the metformin hydrochloride and teneligliptin hydrobromide hydrate tablet.
B. D. Musmade, M. L. Baraskar, V. N. Ghodke, S. G. Bhope, S. Padmanabhan, K. S. Lohar   +5 more
doaj   +7 more sources

Method operable design region for robust RP-HPLC analysis of pioglitazone hydrochloride and teneligliptin hydrobromide hydrate: incorporating hybrid principles of white analytical chemistry and design of experiments

Future Journal of Pharmaceutical Sciences, 2023
Background A combination of pioglitazone hydrochloride with teneligliptin hydrobromide hydrate is used to treat type-2 diabetes. Several chromatographic techniques have been described in the literature for determination of each of these medications ...
Pintu Prajapati, Bageshree Rana, Veera Shakar Pulusu, Shailesh Shah   +3 more
doaj   +5 more sources

Box–Behnken design assisted HPTLC method for quantification of teneligliptin hydrobromide hydrate, metformin hydrochloride and pioglitazone hydrochloride in pharmaceutical dosage form

Discover Chemistry
A Design of expert approach was used to develop and validate a high-performance thin layer chromatography method for simultaneously determining Teneligliptin hydrobromide hydrate, Metformin hydrochloride, and Pioglitazone hydrochloride in tablets.
Patel Kalpana, Babariya Raj, Shah Hitaxi, Tandel Devang, Patel Subhashchandra, Gandhi Tejal   +5 more
doaj   +5 more sources

Development and validation of a UV spectrophotometric method for simultaneous estimation of teneligliptin hydrobromide hydrate and pioglitazone hydrochloride in pharmaceutical dosage form

Future Journal of Pharmaceutical Sciences
Background This study presents the development and validation of a UV spectrophotometric method for the simultaneous estimation of teneligliptin hydrobromide hydrate (TEN) and pioglitazone hydrochloride (PIO) in pharmaceutical dosage forms.
Ravi Shankar Gupta, Akhilesh Tiwari, Sanjeev Kumar Patel, Chandrabose Karthikeyan, Deepak Kumar Gupta, Pranay Soni, Megha Joshi   +6 more
doaj   +5 more sources

Development and Validation of Stability Indicating RP-HPLC method for Teneligliptin Hydrobromide Hydrate

American Journal of PharmTech Research, 2021
Teneligliptin hydrobromide hydrate is a new FDA approved drug for treatment of Diabetes Mellitus. Very few methods have been reported for its identified degradation products and their effects on human.
Girish D. Dahikar, Gayatri Bobade
semanticscholar   +5 more sources

UV Spectrophotometric Method Development and Validation for Determination of Teneligliptin Hydrobromide Hydrate in API and in Pharmaceutical Dosage Form [PDF]

International Journal for Pharmaceutical Research Scholars, 2018
Simple, rapid, sensitive, precise and specific UV Spectrophotometric for the determination of Teneligliptin Hydrobromide Hydrate (THH) in API and pharmaceutical dosage form were developed and validated.
S. A. Kshirsagar, S. B. Mane, Y. S. Hanchate, A. S. Katte, K. V. Kulkarni   +4 more
semanticscholar   +5 more sources

Characterization of impurities in Teneligliptin hydrobromide hydrate by using LCMS/MS and NMR

Research Journal of Pharmacy and Technology, 2020
An accurate and lively LC-MS/MS and NMR analytical methods have been developed for recognition and characterization of key impurities in Teneligliptin. Teneligliptin is an anti-diabetic drug used to treat Diabetes mellitus Type II and three unknown impurities were detected in Teneligliptin bulk drug substance using RP-UFLC method at RT 4.02 min, 5.09 ...
R Maruthi, R.S. Chandan, Anand Kumar Tengli   +2 more
semanticscholar   +6 more sources

Integrated LC–MS/MS bioanalysis for the simultaneous quantification of metformin HCl, pioglitazone HCl, and teneligliptin HBr hydrate in human plasma [PDF]

Journal of Applied Pharmaceutical Research
Background: Combination therapy is widely prescribed in Type II diabetes mellitus to maintain effective glycemic control. The rising use of multidrug regimens demands selective and reliable bioanalytical methods capable of simultaneously quantifying ...
Sejal H. Pandya, Hitesh J. Vekariya
doaj   +4 more sources

An Effective and Time-Saving HPTLC Densitometry Technique for the Measuring of Antidiabetic Triple-Drug Combination: From TLC Spot Formation to Method Validation [PDF]

EPJ Web of Conferences
A precise, rapid, linear & robust High-Performance Thin-Layer Chromatography (HPTLC)-Densitometric was successfully developed and validated method for the simultaneous estimation of a triple antidiabetic drug combination comprising Metformin ...
Pandya Sejal, Vekariya Hitesh J.
doaj   +3 more sources

Analytical method development and validation for simultaneous estimation of Teneligliptin hydrobromide hydrate and Metformin hydrochloride from it's pharmaceutical dosage form by three different UV spectrophotometric methods [PDF]

Journal of Applied Pharmaceutical Science, 2016
Three new UV spectrophotometric methods namely simultaneous equation, absorbance ratio and first derivative (zero crossing) spectroscopic methods were developed and validated for simultaneous estimation of teneligliptin hydrobromide hydrate and metformin hydrochloride in tablet formulation which were simple, sensitive, precise and accurate.
Ashim Sen, Denish Hinsu, Dhanya Sen, Aarti Zanwar, Rajesh Maheshwari, Vikas Chandrakar   +5 more
semanticscholar   +4 more sources