Results 1 to 10 of about 6,599 (152)

Metformin Hydrochloride Significantly Inhibits Rotavirus Infection in Caco2 Cell Line, Intestinal Organoids, and Mice [PDF]

Pharmaceuticals, 2023
Rotavirus is one of the main pathogens that causes severe diarrhea in children under the age of 5, primarily infecting the enterocytes of the small intestine.
Rui Zhang, Dandan Luo, Ruibo Zhao
exaly   +4 more sources

Comparative performance of liquid chromatography and spectrophotometry in determining metformin hydrochloride within pharmaceutical formulations [PDF]

Heliyon
The present study compared the performance of Ultra-high performance liquid chromatography (UHPLC) and UV–Vis spectrophotometry for the quantification of metformin hydrochloride in five commercially available metformin hydrochloride products with ...
Ibrahim K Farh, Mahmoud Mansour
exaly   +4 more sources

Pharmacokinetics of Acetaminophen and Metformin Hydrochloride in Rats After Exposure to Simulated High Altitude Hypoxia [PDF]

Frontiers in Pharmacology, 2021
The pharmacokinetic characteristics of drugs were altered under high altitude hypoxia, thereby affecting the absorption, distribution, metabolism, and excretion of drug. However, there are few literatures on the pharmacokinetic changes of antipyretic and
Jun-bo Zhu, Jun-bo Zhu, Jian-xin Yang, Jian-xin Yang, Yong-qiong Nian, Gui-qin Liu, Ya-bin Duan, Xue Bai, Qian Wang, Yang Zhou, Xue-jun Wang, Ning Qu, Xiang-yang Li   +12 more
doaj   +2 more sources

Formulation and Evaluation of Xanthan Gum Microspheres for the Sustained Release of Metformin Hydrochloride [PDF]

Micromachines, 2023
This work aimed to formulate xanthan gum microspheres for the encapsulation of metformin hydrochloride, according to the process of ionotropic gelation. The obtained microparticles, based on various fractions of xanthan gum (0.5–1.25), were subjected to ...
Madiha Melha Yahoum, Selma Toumi, Hichem Tahraoui, Sonia Lefnaoui, Mohammed Kebir, Abdeltif Amrane, Aymen Amin Assadi, Jie Zhang, Lotfi Mouni   +8 more
doaj   +2 more sources

Role of Environmental Photocatalysts and Organic Matter on the Degradation and Toxicity of Metformin Hydrochloride [PDF]

Toxics
Metformin is the preferred first-line treatment for non-insulin-dependent diabetes mellitus, known for its benefits in cancer suppression, weight loss, and antiketogenic activity.
Rifat Khan, Jaqueline Regalado, Malsha Indeewari Kanaththage, Praveen L. Patidar, Gayan Rubasinghege   +4 more
doaj   +2 more sources

The development of an in-situ biopolymer-based floating gel for the oral delivery of metformin hydrochloride [PDF]

Heliyon, 2023
Diabetes remains a global public health threat because of its increasing prevalence and mortality, especially in people under the age of 25. Metformin hydrochloride (HCl), as recommended by American Diabetes Association in 2022, is the first-line therapy
Ruedeekorn Wiwattanapatapee, Kalayamas Klabklay, Nontawat Raksajit, Worrawee Siripruekpong, Nattawut Leelakanok, Arpa Petchsomrit   +5 more
doaj   +2 more sources

Analysis on the Effect of Metformin Hydrochloride Combined with Insulin Pump for Gestational Diabetes Mellitus [PDF]

Iranian Journal of Public Health, 2022
Background: U To analyze the effect of metformin hydrochloride combined with insulin pump for gestational diabetes mellitus (GDM). Methods: Overall, 216 patients with GDM in Zhangqiu Maternity and Child Care Hospital, Jinan, China from Aug 2018 to Dec
Xinghua Li, Guilian Li, Yan Liu, Fanchun Meng, Lihong Han, Yuanyuan Shao   +5 more
doaj   +2 more sources

In vitro comparative quality evaluation of different brands of metformin hydrochloride tablets available in Mekelle City, Tigray Regional State, Ethiopia [PDF]

BMC Pharmacology and Toxicology
Background Administration of poor-quality medications can result in various effects that jeopardize the drugs’ safety and effectiveness. Due to a lack of adequate post-market surveillance studies, making decisions regarding the quality of medicines ...
Brhane Gebrehiwot Welegebrial, Zenawi Gezae, Samrawit Kidanemariam Gebrekidan, Gebru Gebremeskel Gebrerufael, Haylay Araya Gebregzabiher, Abrahaley Mulu Kidane, Gebretekle Gebremichael Hailesilase   +6 more
doaj   +2 more sources

Evaluation of Seven Different Brands of Metformin Hydrochloride Tablets Available in the Market in Gondar City, Ethiopia [PDF]

Drug, Healthcare and Patient Safety
Adane Flatie Alemu,1 Addisu Afrassa Tegegne,2 Nurahmed Seid Getaw1 1Pharmaceutical Analysis, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia; 2Pharmaceutical Quality Assurance and Regulatory Affairs ...
Flatie Alemu A, Tegegne AA, Getaw NS
doaj   +2 more sources

Multifractal Analysis and Experimental Evaluation of MCM-48 Mesoporous Silica as a Drug Delivery System for Metformin Hydrochloride [PDF]

Biomedicines
Background: This study explored the potential of MCM-48 mesoporous silica matrices as a drug delivery system for metformin hydrochloride, aimed at improving the therapeutic management of type 2 diabetes mellitus. The objectives included the synthesis and
Mousa Sha’at, Maria Ignat, Liviu Sacarescu, Adrian Florin Spac, Alexandra Barsan (Bujor), Vlad Ghizdovat, Emanuel Nazaretian, Catalin Dumitras, Maricel Agop, Cristina Marcela Rusu, Lacramioara Ochiuz   +10 more
doaj   +2 more sources