Results 1 to 10 of about 13,870 (205)

A Simple and Sensitive HPTLC Method for Simultaneous Determination of Metformin Hydrochloride and Sitagliptin Phosphate in Tablet Dosage Form [PDF]

Journal of Chemistry, 2013
A simple, rapid, and precise high-performance thin-layer chromatographic (HPTLC) method for simultaneous estimation of two antidiabetic drugs, metformin hydrochloride and sitagliptin phosphate, in tablet dosage form has been developed and validated ...
Darshana K. Modi, Punit B. Parejiya, Bhavesh H. Patel   +2 more
doaj   +2 more sources

Metformin Hydrochloride Significantly Inhibits Rotavirus Infection in Caco2 Cell Line, Intestinal Organoids, and Mice [PDF]

Pharmaceuticals, 2023
Rotavirus is one of the main pathogens that causes severe diarrhea in children under the age of 5, primarily infecting the enterocytes of the small intestine.
Rui Zhang, Cui Feng, Dandan Luo, Ruibo Zhao, Perumal Ramesh Kannan, Yuebang Yin, Muhammad Zubair Iqbal, Yeting Hu, Xiangdong Kong   +8 more
doaj   +2 more sources

Determination of glibenclamide, metformin hydrochloride and rosiglitazone maleate by reversed phase liquid chromatographic technique in tablet dosage form [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2014
A simple, precise and accurate high performance liquid chromatography (HPLC) method was developed for the simultaneous estimation of metformin hydrochloride, rosiglitazone maleate, glibenclamide present in multicomponent dosage forms ...
Havele Shweta S., Dhaneshwar Sunil R.
doaj   +3 more sources

Pharmacokinetics of Acetaminophen and Metformin Hydrochloride in Rats After Exposure to Simulated High Altitude Hypoxia [PDF]

Frontiers in Pharmacology, 2021
The pharmacokinetic characteristics of drugs were altered under high altitude hypoxia, thereby affecting the absorption, distribution, metabolism, and excretion of drug. However, there are few literatures on the pharmacokinetic changes of antipyretic and
Jun-bo Zhu, Jun-bo Zhu, Jian-xin Yang, Jian-xin Yang, Yong-qiong Nian, Gui-qin Liu, Ya-bin Duan, Xue Bai, Qian Wang, Yang Zhou, Xue-jun Wang, Ning Qu, Xiang-yang Li   +12 more
doaj   +2 more sources

Comparative performance of liquid chromatography and spectrophotometry in determining metformin hydrochloride within pharmaceutical formulations [PDF]

Heliyon
The present study compared the performance of Ultra-high performance liquid chromatography (UHPLC) and UV–Vis spectrophotometry for the quantification of metformin hydrochloride in five commercially available metformin hydrochloride products with ...
Amani Kurdi, Waleed Alhussaini, Abdulrahman Alawaji, Abdullah Alhudathi, Rakan Alharbi, Faisal Binsaleh, Yazeed Alghamidi, Abdulkareem Al Bekairy, Abdulmalik Alkatheri, Imadul Islam, Ibrahim Farh, Ezzeldeen Ghanem, Mahmoud Mansour   +12 more
doaj   +2 more sources

New Route to Metformin Hydrochloride (N,N-dimethylimidodicarbonimidic diamide hydrochloride) Synthesis [PDF]

Molbank, 2008
In this work, microwave (MW) assisted synthesis of metformin hydrochloride was performed on thin layer chromatography (TLC) plates. This versatile, simple and economical green methodology is readily amendable to parallel synthesis of metformin ...
Anvar Shalmashi
doaj   +2 more sources

Formulation and Evaluation of Xanthan Gum Microspheres for the Sustained Release of Metformin Hydrochloride [PDF]

Micromachines, 2023
This work aimed to formulate xanthan gum microspheres for the encapsulation of metformin hydrochloride, according to the process of ionotropic gelation. The obtained microparticles, based on various fractions of xanthan gum (0.5–1.25), were subjected to ...
Madiha Melha Yahoum, Selma Toumi, Hichem Tahraoui, Sonia Lefnaoui, Mohammed Kebir, Abdeltif Amrane, Aymen Amin Assadi, Jie Zhang, Lotfi Mouni   +8 more
doaj   +2 more sources

Role of Environmental Photocatalysts and Organic Matter on the Degradation and Toxicity of Metformin Hydrochloride [PDF]

Toxics
Metformin is the preferred first-line treatment for non-insulin-dependent diabetes mellitus, known for its benefits in cancer suppression, weight loss, and antiketogenic activity.
Rifat Khan, Jaqueline Regalado, Malsha Indeewari Kanaththage, Praveen L. Patidar, Gayan Rubasinghege   +4 more
doaj   +2 more sources

The development of an in-situ biopolymer-based floating gel for the oral delivery of metformin hydrochloride [PDF]

Heliyon, 2023
Diabetes remains a global public health threat because of its increasing prevalence and mortality, especially in people under the age of 25. Metformin hydrochloride (HCl), as recommended by American Diabetes Association in 2022, is the first-line therapy
Ruedeekorn Wiwattanapatapee, Kalayamas Klabklay, Nontawat Raksajit, Worrawee Siripruekpong, Nattawut Leelakanok, Arpa Petchsomrit   +5 more
doaj   +2 more sources

Analysis on the Effect of Metformin Hydrochloride Combined with Insulin Pump for Gestational Diabetes Mellitus [PDF]

Iranian Journal of Public Health, 2022
Background: U To analyze the effect of metformin hydrochloride combined with insulin pump for gestational diabetes mellitus (GDM). Methods: Overall, 216 patients with GDM in Zhangqiu Maternity and Child Care Hospital, Jinan, China from Aug 2018 to Dec
Xinghua Li, Guilian Li, Yan Liu, Fanchun Meng, Lihong Han, Yuanyuan Shao   +5 more
doaj   +2 more sources