Results 21 to 30 of about 6,634 (171)

A Simple and Sensitive HPTLC Method for Simultaneous Determination of Metformin Hydrochloride and Sitagliptin Phosphate in Tablet Dosage Form

Journal of Chemistry, 2013
A simple, rapid, and precise high-performance thin-layer chromatographic (HPTLC) method for simultaneous estimation of two antidiabetic drugs, metformin hydrochloride and sitagliptin phosphate, in tablet dosage form has been developed and validated ...
Darshana K. Modi, Punit B. Parejiya, Bhavesh H. Patel   +2 more
doaj   +1 more source

Comparison of Clinical Efficacy and Safety of Metformin Sustained-Release Tablet (II) (Dulening) and Metformin Tablet (Glucophage) in Treatment of Type 2 Diabetes Mellitus

Frontiers in Endocrinology, 2021
ObjectivesThis study investigated the clinical efficacy and safety of metformin hydrochloride sustained-release (SR) tablet (II) produced by Dulening and the original metformin hydrochloride tablet produced by Glucophage in the treatment of type 2 ...
Li-xin Guo, Guo-en Liu, Li Chen, Hai-fang Wang, Jian Guo, Xian-ling Zheng, Bin-hong Duan, De-zhong Wang, Wei Zhu, Kun Wang, Wan-shou Tan, Qiu Chen, Quan-zhong Li, Jing Yang, Qiu Zhang, Pei-feng Xie, Min-xiang Lei   +16 more
doaj   +1 more source

Spectrophotometric method for analysis of metformin hydrochloride

Indian Journal of Pharmaceutical Sciences, 2009
A simple and sensitive spectrophotometric method has been developed and validated for the estimation of metformin hydrochloride in bulk and in tablet formulation. The primary amino group of metformin hydrochloride reacts with ninhydrin in alkaline medium to form a violet colour chromogen, which is determined spectrophotometrically at 570 nm.
Mubeen, G., Noor, Khalikha
openaire   +3 more sources

Fabrication and Development of Pectin Microsphere of Metformin Hydrochloride [PDF]

ISRN Pharmaceutics, 2012
Purpose. The objective of the proposed work is to evaluate the efficacy of Pectins to qualify them as polymers for designing an oral microsphere for the delivery of selected oral antidiabetic drug-like metformin hydrochloride. Methods. Different Microspheres formulations were prepared by the water in oil (w\o) emulsion solvent evaporation technique and
Banerjee, Pritam, Deb, Jyotirmoy, Roy, Amitava, Ghosh, Amitava, Chakraborty, Prithviraj   +4 more
openaire   +2 more sources

Effect and Safety of Pioglitazone-Metformin Tablets in the Treatment of Newly Diagnosed Type 2 Diabetes Patients with Nonalcoholic Fatty Liver Disease in Shaanxi Province: A Randomized, Double-Blinded, Double-Simulated Multicenter Study

Journal of Diabetes Research, 2023
Objective. The aim of study was to evaluate the effect and safety of pioglitazone-metformin combined treatment in the newly diagnosed type 2 diabetes patients with nonalcoholic fatty liver disease. Methods.
Fu Jianfang, Xiao Wanxia, Gao Xiling, Xu Jing, Yang Wenjuan, Liu Jianrong, He Qingzhen, Ma Kaiyan, Lian Jingxuan, Chen Taixiong, Xu Qian, Li Mengying, Ming Jie, Ji Qiuhe   +13 more
doaj   +1 more source

Bis{[amino(iminiumyl)methyl]urea} tetrakis{2-[(dimethylamino)(iminiumyl)methyl]guanidine} di-μ6-oxido-tetra-μ3-oxido-tetradeca-μ2-oxido-octaoxidodecavanadium(V) tetrahydrate

IUCrData, 2022
The title compound, (C4H12N5)4(C2H7N4O)2[V10O28]·4H2O, is a by-product obtained by reacting ammonium metavanadate(V), metformin hydrochloride and acetic acid in the presence of sodium hypochlorite, at pH = 5.
Aarón Pérez-Benítez, Jorge Luis Ariza-Ramírez, Monserrat Fortis-Valera, Rosa Elena Arroyo-Carmona, María Isabel Martínez de la Luz, Diego Ramírez-Contreras, Sylvain Bernès   +6 more
doaj   +1 more source

Assessment of Taste and Grittiness of Riomet® ER Strawberry, Riomet® ER Grape, Riomet® Cherry, and Metformin Immediate-Release Tablets in Healthy Subjects

Drugs in R&D, 2019
Objective This study was conducted to evaluate the taste and grittiness of two formulations of Riomet® ER (metformin hydrochloride for extended release [ER] oral suspension 100 mg/mL) differing only in their flavoring agents (strawberry and grape) in ...
Allyson C. Marshall, Maureen Damstra, Michael Tuley, Elena L. Schifando   +3 more
doaj   +1 more source

An in vivo pharmacokinetic study of metformin microparticles as an oral sustained release formulation in rabbits

BMC Veterinary Research, 2021
Background Metformin hydrochloride is a biguanide derivative that has been widely used to treat type 2 diabetes in humans. In veterinary medicine, metformin has shown increasing potential for diabetes treatment in different species, such as equids, dogs,
Sihem Bouriche, Angela Alonso-García, Carlos M. Cárceles-Rodríguez, Farouk Rezgui, Emilio Fernández-Varón   +4 more
doaj   +1 more source

Assessment of Alpha-Tocopheryl Acetate and Metformin Hydrochloride as Independent Agents on Human Dermal Fibroblast Viability: Findings from MTT Assay

Althea Medical Journal
Background: Alpha-tocopheryl acetate (Vitamin E) and metformin hydrochloride have been tested as anti-aging compounds at various concentrations. This study aimed to identify the most effective concentrations of alpha-tocopheryl acetate and metformin ...
Nayla Majeda Alfarafisa, Astrid Feinisa Khairani, Achadiyani Achadiyani, Yoan Chou, Fitri Aulia, Muhammad Bintang Firdaus   +5 more
doaj   +1 more source

Determinação condutométrica de cloridrato de metformina em formulações farmacêuticas empregando nitrato de prata como titulante Conductometric determination of metformin hydrochloride in pharmaceutical formulations using silver nitrate as titrant

Química Nova, 2009
A simple, precise, rapid and low-cost conductometric titration method for the determination of metformin hydrochloride (MET) in pharmaceuticals using silver nitrate as titrant is proposed.
Elen Romão Sartori, Willian Toito Suarez, Orlando Fatibello-Filho   +2 more
doaj   +1 more source