Results 31 to 40 of about 6,618 (171)

Influence of Sodium Alginate on Hypoglycemic Activity of Metformin Hydrochloride in the Microspheres Obtained by the Spray Drying

International Journal of Polymer Science, 2016
Alginate microspheres with metformin hydrochloride were prepared by the spray drying method in order to improve residence time of drug in the stomach.
Marta Szekalska, Magdalena Wróblewska, Katarzyna Sosnowska, Katarzyna Winnicka   +3 more
doaj   +1 more source

The application of NIR spectroscopy with chemometric analysis for monitoring the powder blending process [PDF]

Journal of the Serbian Chemical Society, 2014
This paper reports the use of Near Infrared (NIR) spectroscopy as a Process Analytical Technology (PAT) tool for monitoring the metformin hydrochloride and polyvinilpyrolidone (PVP) mixing process, which is the first stage in the tablet ...
Marić Ljiljana B., Jović Branislav D., Petrović Slobodan D., Nikolić Aleksandar M., Homšek Irena J.   +4 more
doaj   +1 more source

The role of metformin hydrochloride in complex therapy of disorders of carbohydrate metabolism in patients with paranoid schizophrenia treated with atypical antipsychotics

Mental Health, 2020
Introduction. According to the literature, mortality among patients with schizophrenia is 1.5 -2 times higher than in the healthy population. One explanation for this is the complication of neuroleptic therapy, which, according to various authors, occurs
Ivan Romash
doaj   +1 more source

Comparative Bioavailability of Metformin Hydrochloride Oral Solution Versus Metformin Hydrochloride Tablets in Fasting Mexican Healthy Volunteers

Advances in Therapy, 2018
Metformin tablets may be challenging to swallow not only for those patients with dysphagia but also for children and the elderly. A metformin solution was developed for easier administration and flexible dose adjustment mantained with the same bioavailability of tablets.
Lourdes, Garza-Ocañas, Jorge, González-Canudas, Eduardo, Tamez-de la O, Christian, Badillo-Castañeda, Marco Vinicio, Gómez-Meza, Yulia, Romero-Antonio, Aarón, Molina-Pérez, Ana Gabriela, Amador-Hernández   +7 more
openaire   +2 more sources

Buried Interface Engineering via a Bifunctional Guanidino‐Carboxyl Molecular Bridge for Enhanced Performance and Stability in Perovskite Solar Cells

EcoEnergy, EarlyView.
A bifunctional molecular bridge using 4‐guanidinobutanoic acid (GCC) is constructed to comprehensively tailor the buried interface of PSCs. By passivating oxygen vacancies, optimizing energy‐level matching, and regulating perovskite crystallization, this strategy simultaneously boosts the power conversion efficiency to 25.37% (20.01% for 13.4 cm2) and ...
Ying Liang, Wenjing Zhou, Yongxuan Zhou, Jiahao Cheng, Wenjian Shen, Guijie Liang, Bin Li, Yong Peng, Zaifang Li, Liu Liu, Jun Yao, Yi‐Bing Cheng, Wangnan Li   +12 more
wiley   +1 more source

Development and evaluation of natural gum-based extended release matrix tablets of two model drugs of different water solubilities by direct compression

Saudi Pharmaceutical Journal, 2016
The study was aimed at developing extended release matrix tablets of poorly water-soluble diclofenac sodium and highly water-soluble metformin hydrochloride by direct compression using cashew gum, xanthan gum and hydroxypropylmethylcellulose (HPMC) as ...
Kwabena Ofori-Kwakye, Kwadwo Amanor Mfoafo, Samuel Lugrie Kipo, Noble Kuntworbe, Mariam El Boakye-Gyasi   +4 more
doaj   +1 more source

Impurity profiling method development and validation of metformin hydrochloride and teneligliptin hydrobromide hydrate in their combination tablet dosage form by using RP-HPLC with UV/PDA detector

Future Journal of Pharmaceutical Sciences, 2021
Background An accurate, precise and robust analytical method was developed for the impurity profiling in the metformin hydrochloride and teneligliptin hydrobromide hydrate tablet.
B. D. Musmade, M. L. Baraskar, V. N. Ghodke, S. G. Bhope, S. Padmanabhan, K. S. Lohar   +5 more
doaj   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Simultaneous Estimation of Metformin Hydrochloride, Pioglitazone Hydrochloride, and Glimepiride by RP-HPLC in Tablet Formulation [PDF]

Journal of Chromatographic Science, 2008
A simple, precise, rapid, and reproducible reversed-phase high-performance liquid chromatography method is developed for the simultaneous estimation of metformin hydrochloride (MET), pioglitazone hydrochloride (PIO), and glimepiride (GLP) present in multicomponent dosage forms. Chromatography is carried out isocratically at 25 degrees C +/- 0.5 degrees
Deepti, Jain, Surendra, Jain, Deepak, Jain, Maulik, Amin   +3 more
openaire   +2 more sources

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source