Results 11 to 20 of about 6,634 (171)

Multifractal Analysis and Experimental Evaluation of MCM-48 Mesoporous Silica as a Drug Delivery System for Metformin Hydrochloride [PDF]

open access: yesBiomedicines
Background: This study explored the potential of MCM-48 mesoporous silica matrices as a drug delivery system for metformin hydrochloride, aimed at improving the therapeutic management of type 2 diabetes mellitus. The objectives included the synthesis and
Mousa Sha’at   +10 more
doaj   +2 more sources

Development and validation of a new spectrophotometric method for simultaneous determination of sitagliptin and metformin hydrochloride in tablet pharmaceutical dosage forms using chemometrics technique in comparison with HPLC

open access: yesEclética Química, 2023
A new, quick, easy, affordable and eco-friendly simultaneous spectrophotometric method for determining a combined sitagliptin and metformin hydrochloride in pharmaceutical formulations was developed and validated using two chemometrics technique.
Maher Ali Almaqtari   +3 more
doaj   +1 more source

Development and Evaluation of Novel Metformin Derivative Metformin Threonate for Brain Ischemia Treatment

open access: yesFrontiers in Pharmacology, 2022
Epidemiologic data reveal that diabetes patients taking metformin exhibit lower incidence of stroke and better functional outcomes during post-stroke neurologic recovery.
Gufang Zhang   +8 more
doaj   +1 more source

Application of Fourier Transform Infrared Spectrophotometry Method for Analysis of Metformin Hydrochloride in Marketed Tablet Dosage Form

open access: yesJurnal Kimia Valensi, 2021
The first line drug given for monotherapy for diabetes mellitus type 2 is metformin hydrochloride, which is a biguanide antihyperglycemic drug. The aim of this research was to develop, validate, and apply the Fourier Transform Infrared spectrophotometry ...
Nerdy Nerdy   +7 more
doaj   +1 more source

Preparation of metformin hydrochloride loaded pH-sensitive hydrogel microspheres

open access: yesJournal of Hebei University of Science and Technology, 2021
In order to avoid the irritation of metformin hydrochloride to the stomach and realize its release in the intestine, with metformin hydrochloride as the main drug and chitosan/sodium alginate as the composite support, the optimal formulation and ...
Yinghua XIE   +3 more
doaj   +1 more source

Determination of glibenclamide, metformin hydrochloride and rosiglitazone maleate by reversed phase liquid chromatographic technique in tablet dosage form [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly, 2014
A simple, precise and accurate high performance liquid chromatography (HPLC) method was developed for the simultaneous estimation of metformin hydrochloride, rosiglitazone maleate, glibenclamide present in multicomponent dosage forms ...
Havele Shweta S., Dhaneshwar Sunil R.
doaj   +1 more source

Formulation and Evaluation of Multilayered Tablets of Pioglitazone Hydrochloride and Metformin Hydrochloride [PDF]

open access: yesJournal of Pharmaceutics, 2014
In the treatment of type 2 diabetes mellitus a continuous therapy is required which is a more complex one. As in these patients there may be a defect in both insulin secretion and insulin action exists. Hence, the treatment depends on the pathophysiology and the disease state.
Chowdary, Y. Ankamma   +2 more
openaire   +2 more sources

Effects of metformin and insulin on gestational diabetes mellitus:

open access: yesPakistan Journal of Pharmaceutical Sciences, 2022
This study was aimed to investigate the combined effects of metformin hydrochloride and insulin during gestational diabetes mellitus. A total 136 patients were randomly divided into study and control group. The control group was treated with insulin only
A dual drugs therapy approach Yalou Jiao   +5 more
doaj   +1 more source

Voltammetric Assay of Metformin Hydrochloride Using Pyrogallol Modified Carbon Paste Electrode

open access: yesActa Chimica Slovenica, 2015
The electrooxidative behavior and determination of metformin hydrochloride, anti-hyperglycemic drug, on a pyrogallol modified carbon paste electrode were investigated using cyclic voltammetry and differential pulse voltammetry.
Ali Kamal Attia   +2 more
doaj   +1 more source

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