Results 91 to 100 of about 34,537 (182)

Real‐world clinical and laboratory changes after switching to two‐drug regimen in HIV‐suppressed individuals: 48 weeks and beyond

HIV Medicine, Volume 27, Issue 8, Page 1241-1252, August 2026.
Abstract Introduction Two‐drug regimens (2DRs) may reduce long‐term drug toxicities and drug‐drug interactions for people with HIV (PWH) on antiretroviral therapy (ART). This study evaluated clinical and laboratory outcomes in PWH who switched from standard ART to dolutegravir and lamivudine (DTG + 3TC) in real‐world settings.
Tommy Hing‐cheung Tang, Ruby Tsz‐shan Kwong, Phillip Chan, Kwok‐wai Lam, Helen Shuk‐ying Chan, Man‐yee Chu, Wilson Lam, Tak‐chiu Wu, Wai‐shing Leung, Sai‐kwong Yung, Wan‐man Ting, Annabel Kai‐tung Choy, Joe Lok‐fung Tung, Jason Ka‐wah Fong, Daniel Kai‐yeung Yeung, Man‐po Lee   +15 more
wiley   +1 more source

Sustained effect of Scotland's HIV pre‐exposure prophylaxis programme on transmission among gay and bisexual men who have sex with men: Population‐based retrospective cohort study

HIV Medicine, Volume 27, Issue 8, Page 1298-1311, August 2026.
Abstract Objectives To evaluate the population‐level impact of seven years of Scotland's HIV pre‐exposure prophylaxis (PrEP) programme among gay, bisexual and other men who have sex with men (GBMSM). Methods National administrative data were used to estimate PrEP coverage and HIV incidence among 35 342 GBMSM attending specialist sexual health services ...
Alan Yeung, Claudia Estcourt, Beth Cullen, Rebecca Metcalfe, Alison Rodger, Dan Clutterbuck, Nicola Steedman, Rak Nandwani, Duncan McCormick, Sharon Hutchinson   +9 more
wiley   +1 more source

Renal function in African women receiving tenofovir disoproxil fumarate as pre‐exposure prophylaxis for HIV during pregnancy and postpartum: A postpartum safety analysis in the CAP016 randomized control trial

HIV Medicine, Volume 27, Issue 8, Page 1333-1343, August 2026.
Abstract Background The effect of tenofovir disoproxil fumarate (TDF) when used as pre‐exposure prophylaxis (PrEP) on renal function in pregnant and postpartum women is understudied. An open‐label clinical trial (CAP016 study) was designed to examine the safety of TDF‐PrEP use during pregnancy and breastfeeding.
Gaysheen Kistan, Tonya Esterhuizen, Megeshinee Naidoo, Alicia C. Desmond, Motshedisi Sebitloane, Dhayendre Moodley   +5 more
wiley   +1 more source

Clinicopathological findings, correlations and outcomes in patients with renal disease and living with antiretroviral‐treated human immunodeficiency virus infection

Internal Medicine Journal, Volume 56, Issue 8, Page 1402-1411, August 2026.
Abstract Background and Aims Antiretroviral therapy (ART) has modified the incidence of renal complications and the patterns of renal disease in people living with Human Immunodeficiency Virus (PLWH). We reviewed (2011–2021) the progress and outcomes (follow‐up to mid‐2025) of 158 such individuals.
Jacqueline A. Evans, Christopher S. B. Sia, Gopal Basu, Orla O’Brien, Alan H. Pham, Rowan G. Walker   +5 more
wiley   +1 more source

Long-Term Real-World Outcomes of Tenofovir Alafenamide in Chronic Hepatitis B: Detailed Analysis of Treatment-Naive and Experienced Patients

The Korean Journal of Gastroenterology
Background/Aims: This study assessed the long-term efficacy and safety of tenofovir alafenamide (TAF) in real-world settings. Methods: Patients who were candidates for TAF treatment and were followed up at 12-week intervals over 192 weeks were enrolled ...
Yu-Xuan Song, Guang-Jun Song, Hui Ma, Bo Feng, Yan-Di Xie   +4 more
doaj   +1 more source

Monitoring of the Cascade of Care in Patients With Chronic HBV in Primary Care Clinics in Australia

Journal of Viral Hepatitis, Volume 33, Issue 8, August 2026.
ABSTRACT To achieve hepatitis B virus (HBV) elimination in Australia, a shift from hospital to community‐based care is needed. This study aimed to describe the prevalence of chronic HBV and uptake of the cascade of care in primary care patients. This prospective cohort study was conducted in 76 urban and regional primary care clinics across Victoria ...
Dina Moussa, Jack Wallace, Jacqui Richmond, Joseph S. Doyle, Long Nguyen, Douglas Boyle, Mark A. Stoové, Jason Asselin, Victoria Polkinghorne, Marvad Ahad, Susanne Glasgow, Kate New, Lena Sanci, Matt Penn, John Furler, Alexander Thompson, Margaret Hellard, Jess Howell   +17 more
wiley   +1 more source

Longitudinal Patterns of Chronic Hepatitis B Care and Treatment Adherence in Australia: A National Linked Data Cohort Study

Journal of Viral Hepatitis, Volume 33, Issue 8, August 2026.
ABSTRACT Current uptake of chronic hepatitis B (CHB) treatment and care in Australia is well below target levels, leading to an ongoing burden of preventable liver disease and cancer. Understanding individual‐level trajectories of care engagement and variation by sociodemographic factors is essential to guide efforts to improve access to and retention ...
Jennifer H. MacLachlan, Nicole Romero, Stacey L. Rowe, Nicole Allard, Benjamin C. Cowie   +4 more
wiley   +1 more source

Prevention of HBV Mother‐To‐Child Transmission (MTCT) Using Targeted HBV Birth Dose, and Treatment of High Viral Load Pregnant Women in Uganda

Journal of Viral Hepatitis, Volume 33, Issue 8, August 2026.
ABSTRACT Hepatitis B virus (HBV) mother‐to‐child transmission (MTCT) remains a major challenge in Uganda, where 43% of births occur at home, and access to timely birth dose (BD) vaccination is limited. We evaluated the impact of combining universal three‐dose (3D) infant vaccination, targeted BD vaccination, and maternal antiviral treatment for high ...
Samantha Hall, Ponsiano Ocama, Danielle Leavelle, Julius Kiwanuka, Brian Lwanga, Joan Nankya‐Mutyoba, Calvin Q. Pan, Christine Namulindwa, Viola Kasone, Rachel Beyagira, Homie Razavi   +10 more
wiley   +1 more source

Beyond Viral Control: Tenofovir's Hidden Impact on Blood-Brain Barrier Endothelial Cells. [PDF]

Microcirculation
Behardien S, Makhathini KB, Willemse C, Fisher D.   +3 more
europepmc   +1 more source

Prevotella bivia Influences Antiretroviral Pharmacokinetics and Viral Replication in an Ex Vivo Vaginal Tissue Model. [PDF]

Clin Transl Sci
Lantz AM, Collins LB, Hirsch EB, Staley C, Nicol MR.   +4 more
europepmc   +1 more source