Results 71 to 80 of about 2,749 (135)

Safety of Prenatal Anti‐Infective Use and Offspring Outcomes: A Panoramic Assessment by Indication, Drug Class, and Exposure Characteristics

iMetaMed, Volume 2, Issue 3, September 2026.
Based on the comprehensive, panoramic assessment of the safety of prenatal anti‐infective use across indications, drug classes, and exposure characteristics, potential safety signals associated with prenatal exposure to several widely used anti‐infective drug classes were identified, including macrolides, metronidazole, tetracyclines, sulfonamides ...
Wenling Wang, Yuezhen Li, Chunrong Liu, Chen Chen, Meng Chen, Lehana Thabane, Xin Sun, Jing Tan   +7 more
wiley   +1 more source

Acute kidney injury KDIGO stage 2 to 3 in HIV-positive patients treated with cART – a case series over 11 years in a cohort of 1,153 patients

Swiss Medical Weekly, 2015
OBJECTIVES: We aimed to explore acute kidney injury (AKI) Kidney Disease Improving Global Guidelines (KDIGO) stage 2 to 3 in a cohort of antiretroviral treated HIV-infected individuals.
Mario Kurz, Felix Burkhalter, Michael Dickenmann, Helmut Hopfer, Michael Mayr, Luigia Elzi, Manuel Battegay   +6 more
doaj   +1 more source

Predicting Oral HIV Pre‐Exposure Prophylaxis Efficacy in Cisgender Women Across Pregnancy and Postpartum

The Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.
Abstract Cisgender women face an increased risk of HIV acquisition during pregnancy and postpartum. Oral pre‐exposure prophylaxis (PrEP) with emtricitabine and tenofovir disoproxil fumarate (F/TDF) is recommended in pregnancy despite limited published pharmacokinetic (PK) and efficacy data during pregnancy.
Yifan Yu, Kristina M. Brooks, Gustavo F. Doncel, Brookie M. Best, Mark A. Marzinke, Mark Mirochnick, Peter L. Anderson, Landon Myer, Connie Celum, Renee Heffron, Jenell Coleman, Dvora L. Joseph Davey, Lanxin Zhang, Max von Kleist, Craig W. Hendrix, Jeremiah D. Momper, Robert Bies, Rachel K. Scott   +17 more
wiley   +1 more source

Dolutegravir Is Associated With Lower Odds of Gestational Diabetes Compared to Other Antiretroviral Therapy Regimens Among Pregnant Women in India: A Cross‐Sectional Analysis

Journal of the International AIDS Society, Volume 29, Issue 9, September 2026.
ABSTRACT Introduction In non‐pregnant adults living with HIV, dolutegravir is associated with weight gain and increased type 2 diabetes risk. In pregnancy, data on the effect of dolutegravir on gestational diabetes (GDM) risk is inconclusive. Data are particularly limited in Asian populations, where diabetes risk is especially high and not always ...
Puja Chebrolu, Farheen Ahmed, Sanjaykumar Tambe, Mallika Alexander, Priyanka Raichur, Aditi Kole, Sonali Kante, Vandana Kulkarni, Nikhil Gupte, Ramesh Bhosale, Shilpa Naik, Amita Gupta, Todd T. Brown, Jyoti S. Mathad   +13 more
wiley   +1 more source

Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report

Viruses, 2010
A first case of clinical tenofovir (TDF) HBV resistance in an HIV/HBV coinfected patient who developed an acute flare of hepatitis B is reported. The clinical course was accompanied by signs of acute liver failure after being on successful HBV treatment ...
Jürgen Kurt Rockstroh, Jan van Lunzen, Stefan Schmiedel, Hüseyin Sirma, Christian Noah, Knud Schewe, Oliver Schildgen   +6 more
doaj   +1 more source

Adding a Prevention Intervention to an Established App: The Blued+ HIV Prevention Pilot Study in Beijing and Chengdu, China

Journal of the International AIDS Society, Volume 29, Issue 9, September 2026.
ABSTRACT Introduction HIV incidence among men who have sex with men (MSM) in China remains high, and the use of effective tools such as pre‐exposure prophylaxis (PrEP) is suboptimal. Smartphone app interventions are promising yet rarely move beyond the research sphere. Rather than inventing stand‐alone apps that rarely come to scale, integrating health
Aaron J. Siegler, Guodong Mi, Fei Yu, Daniel Stegmueller, Kunru Ning, Shi Hao Ernest Koh, Yufen Liu, Kimberly A. Powers, Stefan Baral, Patrick S. Sullivan, Wenting Huang   +10 more
wiley   +1 more source

Comparing Approaches for Estimating Counterfactual HIV Incidence Among Populations With High Vulnerability to HIV in Lima, Peru: A Multi‐Study Comparative Analysis

Journal of the International AIDS Society, Volume 29, Issue 9, September 2026.
ABSTRACT Introduction The availability of highly efficacious HIV pre‐exposure prophylaxis (PrEP) makes it unethical or infeasible to conduct inactive/placebo‐controlled trials to evaluate new HIV prevention options. As a result, randomized active‐control non‐inferiority trials are typically employed; however, they require large sample sizes and ...
Fei Gao, Sayan Dasgupta, Siavash Pasalar, Qi Wang, Ricardo Alfaro, Delia Pinto‐Santini, Thiago S. Torres, Jorge Sanchez, Javier R. Lama, Valdilea G. Veloso, Michal Juraska, Robinson Cabello, Jorge O. Alarcon, Beatriz Grinsztejn, Carlos F. Caceres, James F. Rooney, Ann Duerr   +16 more
wiley   +1 more source

Understanding Adolescent Anti‐Retroviral Therapy Use in the BREATHER‐Plus Trial: Qualitative Findings From South Africa and Uganda

Journal of the International AIDS Society, Volume 29, Issue 9, September 2026.
ABSTRACT Introduction The BREATHER‐Plus trial was an open‐label, randomized non‐inferiority trial comparing weekends off antiretroviral therapy (ART) (short cycle therapy [SCT]) with daily oral ART (continuous therapy [CT]) for adolescents aged 12–19 years. We present findings from the qualitative sub‐study on the factors influencing trial participants’
Londiwe Shandu, Stella Namukwaya, Tamlyn Carmin Seunanden, Nothando Ngwenya, Moherndran Archary, Cissy Kityo, Deborah Ford, Sarah L. Pett, Adeodata R. Kekitiinwa, Sarah Bernays, Janet Seeley, the BREATHER‐Plus trial team   +11 more
wiley   +1 more source

Effect of a Peer Support Intervention for Oral Pre‐Exposure Prophylaxis Uptake and Adherence Among Adolescent Girls and Young Women at Risk of HIV Acquisition in Kampala, Uganda: A Randomized Controlled Trial

Journal of the International AIDS Society, Volume 29, Issue 9, September 2026.
ABSTRACT Introduction Daily oral pre‐exposure prophylaxis (PrEP) use remains low among adolescent girls and young women (AGYW). We evaluated whether a peer support intervention improved daily oral PrEP uptake and adherence among AGYW at high risk of HIV acquisition in Kampala, Uganda.
Yunia Mayanja, Andrew Abaasa, Kenneth Roger Katumba, Matthew Spinelli, Bernard Kikaire, Monica Gandhi, Kyriaki Kosidou, Anna Mia Ekstrom, Eugene Ruzagira   +8 more
wiley   +1 more source

Identification of a Novel Small Molecule Facilitating HIV Elimination by the “Shock‐And‐Kill” Approach

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Antiretroviral therapy (ART) has markedly improved the prognosis of people living with HIV (PLWH); however, latent viral reservoirs remain a major barrier to a cure. The “Shock and Kill” strategy aims to reactivate latent provirus with latency‐reversing agents (LRAs) and subsequently eliminate the infected cells, yet most LRAs characterized to
Yuichiro Hara, Haruki Kitamura, Kouki Matsuda, Chieko Fujisaki, Sayaka Sukegawa, Kosuke Tanimoto, Kenji Maeda, Hiroaki Takeuchi   +7 more
wiley   +1 more source