Results 61 to 70 of about 34,537 (182)

Early Onset of Tenofovir-Induced Renal Failure: Case Report and Review of the Literature

The Scientific World Journal, 2007
Tenofovir is an acyclic nucleotide analogue reverse transcriptase inhibitor that is commonly prescribed as part of a highly active antiretroviral therapy (HAART) regimen in HIV-infected patients.
Shilpa M. Patel, Teresa R. Zembower, Frank Palella, Yashpal S. Kanwar, Shubhada N. Ahya   +4 more
doaj   +1 more source

Gaps in the Cascade of Care Contribute to Poor Liver Cancer Outcomes Among People Living With Hepatitis B: A Multicenter Observational Cohort Study

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Chronic hepatitis B virus (HBV) remains a major cause of hepatocellular carcinoma (HCC) in Australia, despite the availability of effective, subsidized antiviral therapy. We aimed to describe the clinical characteristics, HBV care cascade, and outcomes among people with HBV‐related HCC in Victoria, Australia.
Dina Moussa, Joan Ericka Flores, Michael Macisaac, Jack Wallace, Joseph Doyle, Marno Ryan, Thai Hong, Brett Knowles, Adrian Fox, Ashu Jhamb, Tom Sutherland, Stuart Roberts, William Kemp, Ammar Majeed, Marie Sinclair, Rohit Sawhney, Stephen Bloom, Amanda Nicoll, Zina Valaydon, Gauri Mishra, Sid Sood, Diana Lewis, A. Thompson, J. Howell   +23 more
wiley   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Altered Pharmacokinetics and Delayed Sputum Conversion in Tuberculosis Patients Co‐Infected With HIV

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background HIV co‐infection affects host responses and pharmacokinetics (PK) of tuberculosis (TB) treatment. This study assessed the PK of first‐line anti‐TB drugs and clinical outcomes in patients with and without HIV co‐infection. Methods In this prospective observational study, 61 adults with sputum‐positive pulmonary TB, either confirmed ...
Aung Pyae Phyo, Richard M. Hoglund, Makoto Saito, Sein Sein Thi, Lei Lei Swe, Palang Chotsiri, Htet Ko Ko Aung, Win Pa Pa Tun, Banyar Maung Maung, Chanapat Pateekham, Wanitda Watthanaworawit, Gornpan Gornsawun, Nicholas J. White, Francois Nosten, Joel Tarning   +14 more
wiley   +1 more source

Analysis of minimum target prices for production of entecavir to treat hepatitis B in high- and low-income countries

Journal of Virus Eradication, 2015
Background: In 2013, an estimated 686,000 people died from hepatitis B virus (HBV) infection worldwide. Mass treatment programmes for hepatitis B will require very low drug costs.
Andrew Hill, Dzintars Gotham, Graham Cooke, Sanjay Bhagani, Isabelle Andrieux-Meyer, Jennifer Cohn, Joseph Fortunak   +6 more
doaj   +1 more source

Validation of an UHPLC–MS/MS Assay for the Quantification of Isoniazid and Four Major Metabolites in Human Plasma

Biomedical Chromatography, Volume 40, Issue 9, September 2026.
ABSTRACT Isoniazid (INH) is a key component of tuberculosis treatment regimens but is also associated with hepatotoxicity. This toxicity is mediated in part by its metabolites, but some degrade rapidly in plasma. A rapid freeze/thaw process with a methanol protein precipitation extraction was developed to slow the rapid degradation of acetylisoniazid ...
David Nerguizian, Brandon Klein, Farah Abdelmawla, Joe Gomez, Peter L. Anderson, Lane Bushman, Kristina M. Brooks   +6 more
wiley   +1 more source

The Impact of Chronic Hepatitis D Virus Infection on Health‐Related Quality of Life and Fatigue: A Real‐World International Study

Journal of Viral Hepatitis, Volume 33, Issue 9, September 2026.
ABSTRACT As little is known about the disease burden of chronic hepatitis D virus (HDV) infection, this study examined health‐related quality of life (HRQoL) and fatigue at different disease stages. This was a real‐world quantitative cross‐sectional survey of patients in Germany, Italy, Spain and the USA.
P. Lampertico, R. G. Gish, N. Reau, H. Wedemeyer, M. Buti, A. Kaushik, A. Yehoshua, C. Burk, L. Mirams, H. Ellis, T. Taylor‐Whiteley, M. Rock   +11 more
wiley   +1 more source

Switching to Tenofovir Therapy Versus Continuation of Entecavir for Patients With Hepatitis B Virus Infection: A Systematic Review and Meta‐Analysis

JGH Open
Background Hepatitis B virus (HBV) infection causes liver disease, including hepatocellular carcinoma. Controlling viral activity is crucial to reducing complications.
Muhammad Shahzil, Ammad Javaid Chaudhary, Talha Kashif, Ali Akram Qureshi, Anza Muhammad, Faiza Khan, Muhammad Saad Faisal, Muhammad Ali Khaqan, Hassam Ali, Yara Dababneh, Dilip Moonka   +10 more
doaj   +1 more source

Characterising Hepatitis D Virus in the UK From 2011 to 2021

Journal of Viral Hepatitis, Volume 33, Issue 9, September 2026.
ABSTRACT Little is known about hepatitis B virus (HBV) and Hepatitis D virus (HDV) coinfection in the UK. HDV screening is recommended among all individuals with HBV, with coinfection associated with increased disease progression. Using data on HDV testing, shared by 11 laboratories in the UK who reported undertaking HDV testing, and national testing ...
R. Simmons, S. Ijaz, R. Jackson, K. Jack, R. Mulongeni, R. Raghu, A. Riddell, A. Elsharkawy, A. Uriel, A. Koffas, A. Chaika, A. Lawson, A. Cole, A. McEwan, A. Brown, B. Stone, C. Levick, D. Byrne, D. Forton, D. MacDonald, D. Forde, E. Nastouli, E. Barnes, E. Sumner, E. Page, I. Carey, F. J. Vilar, J. Maggs, J. Collier, J. Shepherd, K. Agarwal, K. Bicknell, K. Ala, K. Dear, L. Ratcliffe, M. Bruce, H. Zhang, L. Rivett, M. Maes, M. Ankcorn, M. Aldersley, M. Prince, M. Lemoine, M. Foxton, M. Wright, M. Cramp, M. Wiselka, N. Easom, P. Richardson, R. Gunson, R. Herbert, R. Blackwell, R. Jelley, R. Aspinall, R. Simpson, R. Clewes, S. Ahmad, S. Mcpherson, S. Ryder, S. Verma, T. Lampejo, V. Sathyanarayana, W. Gelson, D. Leeman, M. Desai, S. Mandal, P. T. Kennedy, W. L. Irving   +67 more
wiley   +1 more source

Validation of a Point‐Of‐Care Ultrasound for Hepatitis Among Front‐Line Healthcare Workers Managing Chronic Hepatitis B Virus Infection in Zambia

Journal of Viral Hepatitis, Volume 33, Issue 9, September 2026.
ABSTRACT To close gaps in implementing care of people with hepatitis B virus (HBV) infection in resource‐limited settings, we evaluated the accuracy of a novel liver point‐of‐care ultrasound (POCUS) protocol for hepatitis (PUSH) among front‐line non‐radiology healthcare workers in Zambia. At University Teaching Hospital in Lusaka, Zambia, from March to
Costanza Bertoni, Annie Kanunga, Edford Sinkala, Enock Syabbalo, Helen Chitundu, Alick Chikwezi, Carolyn Chibundi, Guy K. Muula, Samuel Bosomprah, Nicolò Capra, Riccardo Lolatto, Giulia Morsica, Antonella Castagna, Claudia Wallrauch, Tom Heller, Michael J. Vinikoor   +15 more
wiley   +1 more source