Results 161 to 170 of about 19,810 (202)

Emtricitabine + Tenofovir Alafenamide for the Treatment of HIV

Expert Opinion on Pharmacotherapy, 2017
Tenofovir alafenamide is a new oral prodrug of tenofovir resulting in relatively low plasma levels and rapid uptake into peripheral blood mononuclear cells in its active form. The United States Food and Drug Administration has now approved this drug coformulated with elvitegravir/cobicistat/emtricitabine, rilpivirine/emtricitabine and emtricitabine ...
Eric S Daar
exaly   +3 more sources

Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate, Coformulated With Elvitegravir, Cobicistat, and Emtricitabine, for Initial Treatment of HIV-1 Infection: Two Randomised, Double-Blind, Phase 3, Non-Inferiority Trials [PDF]

Lancet, The, 2015
Background Tenofovir disoproxil fumarate can cause renal and bone toxic effects related to high plasma tenofovir concentrations. Tenofovir alafenamide is a novel tenofovir prodrug with a 90% reduction in plasma tenofovir concentrations.
Daniel Podzamczer, Paul E Sax, Scott McCallister   +2 more
exaly   +3 more sources

Twenty-Eight Day Safety, Antiviral Activity, and Pharmacokinetics of Tenofovir Alafenamide for Treatment of Chronic Hepatitis B Infection

Journal of Hepatology, 2015
BACKGROUND & AIMS: Tenofovir alafenamide, a phosphonate prodrug of tenofovir with greater plasma stability than tenofovir disoproxil fumarate, provides efficient delivery of active drug to hepatocytes at reduced systemic tenofovir exposures. METHODS: Non-
Stephen D Ryder, Graham R Foster, Kosh Agarwal   +2 more
exaly   +2 more sources

Tenofovir alafenamide

Reactions Weekly, 2022
  +4 more sources

Pharmacokinetics of Tenofovir Alafenamide, Tenofovir, and Emtricitabine Following Administration of Coformulated Emtricitabine/Tenofovir Alafenamide in Healthy Japanese Subjects

Clinical Pharmacology in Drug Development, 2018
AbstractA fixed‐dose combination of tenofovir alafenamide (TAF) and emtricitabine (FTC) is available in 2 tablet strengths in Japan (FTC/TAF 200/10 mg and FTC/TAF 200/25 mg). These are used once daily in combination with other antiretroviral agents for the treatment of human immunodeficiency virus type 1 infection.
Hiroyuki, Yamada, Takuma, Yonemura, Takanori, Nemoto, Noriko, Ninomiya, Shin, Irie   +4 more
openaire   +2 more sources

Tenofovir-alafenamide

Reactions Weekly
  +5 more sources

Fanconi Syndrome and Tenofovir Alafenamide

Annals of Internal Medicine, 2019
Hortensia, Álvarez, Josep M, Llibre
openaire   +4 more sources

Tenofovir alafenamide

Reactions Weekly, 2018
openaire   +2 more sources

Tenofovir alafenamide

Reactions Weekly, 2023
openaire   +1 more source

[Tenofovir alafenamide fumarate - a new generation of tenofovir].

Klinicka mikrobiologie a infekcni lekarstvi, 2018
Antiretroviral therapy as a life-long treatment has to meet the criteria of maximum efficiency while maintaining the highest possible level of safety and tolerance. Tenofovir disoproxil fumarate (TDF) is an antiretroviral drug with an excellent effect of virological suppression.
Svatava, Snopková, Kateřina, Havlíčková, Petr, Husa   +2 more
openaire   +1 more source