Results 11 to 20 of about 7,224 (167)
Tenofovir alafenamide fumarate
Antiviral Therapy, 2022 Tenofovir alafenamide fumarate is a lipophilic prodrug of tenofovir which is preferentially metabolized in lymphatic tissue resulting in high concentrations of tenofovir (TFV) and its active diphosphate metabolite inside the cells that replicate HIV. Due
Andrew Cheng, William Lee
exaly +4 more sources
Co-crystals, Salts or Mixtures of Both? The Case of Tenofovir Alafenamide Fumarates
Pharmaceutics, 2020 Tenofovir alafenamide fumarate (TAF) is the newest prodrug of tenofovir that constitutes several drug products used for the treatment of HIV/AIDS. Although the solid-state properties of its predecessor tenofovir disoproxil fumarate have been investigated
Zdenko Cäsar +2 more
exaly +3 more sources
Journal of the International AIDS SocietyIntroduction Among many antiretroviral drugs, tenofovir alafenamide is used extensively in combination regimens of tenofovir/emtricitabine or tenofovir/emtricitabine/bictegravir.
Jeong-Ju Yoo
exaly +2 more sources
Urine Assay to Measure Tenofovir Concentrations in Patients Taking Tenofovir Alafenamide
Frontiers in Pharmacology, 2020 Background: HIV pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine is effective when taken daily. Previously, we developed a urine assay capable of detecting the prodrug tenofovir (TFV) in patients taking tenofovir disoproxil fumarate (TDF ...
Karam Mounzer +2 more
exaly +3 more sources
EBioMedicine, 2016 Background: Initiation of antiretroviral therapy (ART) and subsequent virologic suppression reduces immune activation and systemic inflammation. Methods: We examined longitudinal changes in biomarkers of monocyte activation (sCD14, sCD163), and systemic (
Scott Mccallister +2 more
exaly +3 more sources
Comparative analysis of tenofovir alafenamide and entecavir on renal function and serum lipids in liver transplant recipients: a controlled retrospective cohort study [PDF]
BMC GastroenterologyBackground Antiviral treatments can impact serum lipids as well as kidney function. We conducted a retrospective observational study with a 48-month follow-up period, involving liver transplant recipients receiving either entecavir or tenofovir ...
Hüseyin Döngelli +7 more
doaj +2 more sources
Frontiers in Pharmacology, 2023 Background/aim: Tenofovir amibufenamide (TMF) has shown potent antiviral efficacy in randomized clinical studies. This study aimed to reveal the effectiveness and safety of tenofovir amibufenamide in the real world and compared tenofovir amibufenamide to
Lanqing Li +7 more
doaj +1 more source
International Journal of Infectious Diseases, 2021 : Objective: To investigate changes in weight following the initiation of antiretroviral therapy in treatment-naïve Asian people living with human immunodeficiency virus (PLWH).
Naokatsu Ando +7 more
doaj +1 more source
Frontiers in Medicine, 2022 BackgroundTenofovir alafenamide fumarate has been used in late pregnancy; however, no data exist regarding its safety and effectiveness in early and middle pregnancy for mothers with hepatitis B virus infection.AimsTo design a prospective study to ...
Ruochan Chen +13 more
doaj +1 more source
Future Journal of Pharmaceutical Sciences, 2022 Background The present research article involves the simultaneous determination of Tenofovir alafenamide, Darunavir, Emtricitabine and Cobicistat in bulk as well as in tablet dosage form using high performance liquid chromatography. Result The separation
Challamalla Pavani, E. Susithra
doaj +1 more source