An autoimmune disease prevented by anti-retroviral drugs [PDF]
Background Both Aicardi-Goutières syndrome, a Mendelian mimic of congenital infection, and the autoimmune disease systemic lupus erythematosus can result from mutations in the gene encoding the enzyme Trex1.
Gabriele B Beck-Engeser +2 more
core +3 more sources
Jing Li,1 Donghua Zhang,1 Xinxin Zhang1,2 1Department of Infectious Diseases, Research Laboratory of Clinical Virology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Sino-French Research ...
Li J, Zhang D, Zhang X
doaj
Pharmacokinetics and Pharmacodynamics of the Reverse Transcriptase Inhibitor Tenofovir and Prophylactic Efficacy against HIV-1 Infection [PDF]
Antiviral pre-exposure prophylaxis (PrEP) through daily drug administration can protect healthy individuals from HIV-1 infection. While PrEP was recently approved by the FDA, the potential long-term consequences of PrEP implementation remain entirely ...
Duwal, Sulav +2 more
core +2 more sources
Dyslipidemia in chronic hepatitis B patients on tenofovir alafenamide: Facts and puzzles [PDF]
Hung-Yao Lin, Tai-Chung Tseng
doaj +1 more source
Daily HIV pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate-emtricitabine reduced Streptococcus and increased Erysipelotrichaceae in rectal microbiota. [PDF]
Daily PrEP is highly effective at preventing HIV-1 acquisition, but risks of long-term tenofovir disoproxil fumarate plus emtricitabine (TDF-FTC) include renal decline and bone mineral density decrease in addition to initial gastrointestinal side effects.
Dubé, Michael P +5 more
core +3 more sources
An Asymptomatic Lesion on the Penis
JEADV Clinical Practice, Volume 5, Issue 1, Page 309-311, March 2026.
Brandon Tan +3 more
wiley +1 more source
The effect of Tenofovir on renal function among Ugandan adults on long-term antiretroviral therapy: a cross-sectional enrolment analysis. [PDF]
BACKGROUND: WHO recommends using Tenofovir containing first line antiretroviral therapy (ART), however, Tenofovir has been reported to be associated with renal impairment and dysfunction.
CoLTART study team +7 more
core +1 more source
An association between K65R and HIV-1 subtype C viruses in patients treated with multiple NRTIs [PDF]
Objectives: HIV-1 subtype C might have a greater propensity to develop K65R mutations in patients with virological failure compared with other subtypes. However, the strong association between viral subtype and confounding factors such as exposure groups
Churchill, D +13 more
core
Background and objectives: Low bone mineral density (BMD) is a recognized complication in people living with HIV (PLHIV) that remains under-addressed, particularly in Malaysia.
Muhamad Riduan Daud +7 more
doaj +1 more source
HIV and CKD in the Tenofovir Era: A Prospective Parallel-Group Cohort Study From Tanzania
Rationale & Objective: Longitudinal research on chronic kidney disease (CKD) in sub-Saharan Africa is sparse, especially among people living with HIV (PLWH).
Nicholas L.S. Roberts +11 more
doaj +1 more source

