ABSTRACT BV + AVD is increasingly used for frontline treatment of stage III/IV cHL. Young adults and adults (Ya&A) were the most common patients treated with BV + AVD in clinical trials but have not been studied in non‐trial settings. We conducted a real‐life study in secondary and tertiary cancer centers to evaluate the PFS in 18–59 years aged ...
Marco Picardi +28 more
wiley +1 more source
Objectives: Tenofovir disoproxil fumarate (TDF) has been reported to cause nephrotoxicity necessitating cessation in some patients. No information is available on the nephrotoxic effect of TDF in Omani or regional patients with HIV infection.
Kowthar Salman Hassan, Abdullah Balkhair
doaj +1 more source
Development and validation of a stability-indicating lc method for the determination of tenofovir disoproxil fumarate in pharmaceutical formulation [PDF]
The present study describes the degradation of tenoforvir disoproxil fumarate (teno) under different prescribed stressconditions (hydrolysis, oxidation, dry and wet heat and photolysis) following the International Conference on Harmonization and ...
Shweta Havele, Sunil R. Dhaneshwar
core
Polypharmacy in HIV: Rethinking what counts and why it matters
Abstract Polypharmacy, the concurrent use of multiple medications, presents a growing challenge in HIV care as people living with HIV age and experience earlier onset of age‐related co‐morbidities. However, how polypharmacy is defined and assessed in HIV research remains inconsistent.
Luxsena Sukumaran +6 more
wiley +1 more source
The role of drug transporters in the kidney: lessons from tenofovir [PDF]
Tenofovir disoproxil fumarate, the prodrug of nucleotide reverse transcriptase inhibitor tenofovir, shows high efficacy and relatively low toxicity in HIV patients.
Moss, DM, Neary, M, Owen, A
core +2 more sources
Informal PrEP use in Greece: The long, hard road to formal programmatic implementation
Abstract Objectives Pre‐exposure prophylaxis (PrEP) with antiretroviral drugs (ARVs) is a highly effective HIV prevention strategy. Although the European Medicines Agency approved oral PrEP in 2016 and the World Health Organization (WHO) has since recommended simplified and person‐centred delivery models, implementation remains inconsistent across ...
Konstantinos Protopapas +3 more
wiley +1 more source
Persistent risk for new, subsequent new and recurrent hepatocellular carcinoma despite successful anti-hepatitis B virus therapy and tumor ablation: The need for hepatitis B virus cure. [PDF]
Hepatitis B virus (HBV) is one of the most significant hepatocarcinogens. The ultimate goal of anti-HBV treatment is to prevent the development of hepatocellular carcinoma (HCC).
Coben, Robert M. +7 more
core +1 more source
An Asymptomatic Lesion on the Penis
JEADV Clinical Practice, EarlyView.
Brandon Tan +3 more
wiley +1 more source
Abstract Cryoglobulinemia (CG) is defined by the presence of serum immunoglobulins that precipitate below 37°C and redissolve upon rewarming. It is classified into three types based on immunoglobulin composition. Type I, a rare form, involves monoclonal IgM or IgG and is linked to lymphoproliferative disorders.
Anna Linda Zignego +7 more
wiley +1 more source
Improved central nervous system symptoms in people with HIV without objective neuropsychiatric complaints switching from Efavirenz to Rilpivirine containing cART [PDF]
Objective: Occult central nervous system (CNS) symptoms not recognized by people living with HIV (PLWH) receiving efavirenz or their clinicians could occur and impact people’s quality of life. The aim of this study was to determine whether CNS parameters
Alagaratnam, Jasmini +7 more
core +1 more source

