Results 41 to 50 of about 175,313 (264)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Low-Level Laser and TENS Therapy Assessment for the Treatment of Temporomandibular Joint Disorder

Journal of Pharmacy and Bioallied Sciences
Introduction: The most prevalent conditions in the population are temporomandibular disorders (TMDs), which are linked to a number of morbidities. A number of treatment options have been proposed, and some of the most successful ones include low-level ...
Silpiranjan Mishra, Atul Anand Bajoria, NC Sangamesh, Ajit Kumar Swain, Sanjay Kumar Sahoo, Abinash Mohapatra   +5 more
doaj   +1 more source

Comparative Use of Electromyography in the Evaluation of Electroacupuncture and Transcutaneous Electrical Neural Stimulation (TENS) Effect on Regeneration of Sciatic Nerve in Dog [PDF]

Iranian Journal of Veterinary Surgery, 2007
Objective-To determine the effect of Electroacupuncture and Transcutaneous Electrical Neural Stimulation on Regeneration of Sciatic Nerve in Dog   Design - Experimental in vivo study. Animals - A total of 15 adult male mixed bred dogs, weighing 26±2.6 Kg/
Davood Sharifi, Jalal Bakhtiari, Masud Sarhadi, Bahram Dadmehr, Hamid Reza Tagavi   +4 more
doaj  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Functional and Radiological Outcomes of Pediatric Both-Bone Forearm Fractures Treated with Titanium Elastic Nailing System: A Prospective Observational Study

Journal of Pharmacy and Bioallied Sciences
Background: Diaphyseal fractures of the radius and ulna are among the most frequent long-bone injuries in children. While conservative management is often effective in stable fractures, surgical fixation is preferred for unstable or displaced fractures ...
A. Karthick, M. Dharun Kumar, Ashin Khan, Panneerselvam Periasamy   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Tonic Investigation Concept of Cervico-vestibular Muscle Afferents

International Archives of Otorhinolaryngology, 2017
Introduction Interdisciplinary research has contributed greatly to an improved understanding of the vestibular system. To date, however, very little research has focused on the vestibular system's somatosensory afferents. To ensure the diagnostic quality
Linda Josephine Dorn, Annabelle Lappat, Winfried Neuhuber, Hans Scherer, Heidi Olze, Matthias Hölzl   +5 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source