Results 71 to 80 of about 1,121 (233)

Chaotic Binarization Schemes for Solving Combinatorial Optimization Problems Using Continuous Metaheuristics

open access: yesMathematics
Chaotic maps are sources of randomness formed by a set of rules and chaotic variables. They have been incorporated into metaheuristics because they improve the balance of exploration and exploitation, and with this, they allow one to obtain better ...
Felipe Cisternas-Caneo   +5 more
doaj   +1 more source

A Novel Chaotic Interior Search Algorithm for Global Optimization and Feature Selection

open access: yesApplied Artificial Intelligence, 2020
Interior Search Algorithm (ISA) is a recently proposed metaheuristic inspired by the beautification of objects and mirrors. However, similar to most of the metaheuristic algorithms, ISA also encounters two problems, i.e., entrapment in local optima and ...
Sankalap Arora   +2 more
doaj   +1 more source

Anti‐Apoptotic and Neurite‐Protective Nanomedicine Augments Embryonic Stem Cells‐Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery

open access: yesAdvanced Science, EarlyView.
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen   +14 more
wiley   +1 more source

Fractal tiles induced by tent maps

open access: yesDiscrete and Continuous Dynamical Systems
In the present article, we deal with geometrical objects induced by the tent maps associated with special Pisot numbers that we call tent-tiles. They are compact subsets of the one-, two-, or three-dimensional Euclidean space, depending on the particular special Pisot number.
Scheicher, Klaus   +2 more
openaire   +2 more sources

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

open access: yesAdvanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai   +7 more
wiley   +1 more source

Resolvin D5 Inhibits CXCL8 Expression in Colonic Epithelial Cells Through Activating GPR101 to Impede Neutrophil Recruitment and Consequently Alleviate Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...
Pengxiang Guo   +9 more
wiley   +1 more source

Exploring Simplicity Bias in 1D Dynamical Systems

open access: yesEntropy
Arguments inspired by algorithmic information theory predict an inverse relation between the probability and complexity of output patterns in a wide range of input–output maps. This phenomenon is known as simplicity bias.
Kamal Dingle   +3 more
doaj   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

A Novel Chaotic Map and an Improved Chaos-Based Image Encryption Scheme

open access: yesThe Scientific World Journal, 2014
In this paper, we present a novel approach to create the new chaotic map and propose an improved image encryption scheme based on it. Compared with traditional classic one-dimensional chaotic maps like Logistic Map and Tent Map, this newly created ...
Xianhan Zhang, Yang Cao
doaj   +1 more source

SR‐B1‐Mediated Transplacental Transfer of Hydrophobic Toxicants Disrupts Fetal Development During Barriergenesis

open access: yesAdvanced Science, EarlyView.
This study maps the spatiotemporal distribution of hydrophobic toxicants and endogenous metabolites in the developing placenta and fetus. By integrating mass spectrometry imaging with snRNA‐seq, we identify SR‐B1 as a key transporter driving early‐gestation xenobiotic transfer and reveal a critical exposure window associated with persistent fetal ...
Yixuan Huang   +10 more
wiley   +1 more source

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