Results 21 to 30 of about 234 (110)
The Positive Role and Mechanism of Herbal Medicine in Parkinson's Disease. [PDF]
Oxid Med Cell Longev, 2021 Parkinson’s disease (PD) is a complex neurodegenerative disease, manifested by the progressive functional impairment of the midbrain nigral dopaminergic neurons. Due to the unclear underlying pathogenesis, disease‐modifying drugs for PD remain elusive.
Yin R +7 more
europepmc +2 more sources
The Effects of Yuan-Zhi Decoction and Its Active Ingredients in Both In Vivo and In Vitro Models of Chronic Cerebral Hypoperfusion by Regulating the Levels of Aβ and Autophagy. [PDF]
Evid Based Complement Alternat Med, 2020 Chronic cerebral hypoperfusion (CCH) is closely related to the occurrence of Alzheimer’s disease (AD) in the elderly. CCH can induce overactivation of autophagy, which increases the deposition of amyloid‐β (Aβ) plaques in the brain, eventually impairing the cognitive function. Yuan‐Zhi decoction (YZD) is a traditional Chinese medicine (TCM) formulation
Liu Y +5 more
europepmc +2 more sources
CNS Neuroscience &Therapeutics, Volume 29, Issue 8, Page 2045-2059, August 2023., 2023 Potential mechanisms of aromatic plant extracts for the treatment of Alzheimer's disease. Abstract Aims The aim of this review is to outline recent advancements in the application and mechanistic studies of aromatic plant extracts in Alzhermer`s disease (AD) to demonstrate their value in the management of this disease.
Yue Ma +7 more
wiley +1 more source
Chinese medicine in the treatment of autoimmune hepatitis: Progress and future opportunities
Animal Models and Experimental Medicine, Volume 5, Issue 2, Page 95-107, April 2022., 2022 Generalized relations between traditional Chinese medicines and different animal models for AIH. Abstract Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease occurring in individuals of all ages with a higher incidence in females and characterized by hypergammaglobulinemia, elevated serum autoantibodies and histological features of ...
Jia Liu, Zhi Ma, Han Li, Xiaojiaoyang Li
wiley +1 more source
Herbal Active Ingredients: Potential for the Prevention and Treatment of Acute Lung Injury
BioMed Research International, Volume 2021, Issue 1, 2021., 2021 Acute lung injury (ALI) is a life‐threatening clinical syndrome with high morbidity and mortality. The main pathological features of ALI are increased alveolar‐capillary membrane permeability, edema, uncontrolled migration of neutrophils to the lungs, and diffuse alveolar damage, resulting in acute hypoxemic respiratory failure.
Wen-Ying Yu +5 more
wiley +1 more source
Research Progress on the Antiosteoarthritic Mechanism of Action of Natural Products
Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021 Background. Osteoarthritis (OA) is a clinical joint degenerative disease, the pathogenic factors of which include age, obesity, and mechanical injury. Its main pathological features include cartilage loss, narrowing of joint space, and osteophyte formation. At present, there are a variety of treatment methods for OA.
Mingzhu Gao +6 more
wiley +1 more source
The Effects of Different Factors on the Behavior of Neural Stem Cells. [PDF]
Stem Cells Int, 2017 The repair of central nervous system (CNS) injury has been a worldwide problem in the biomedical field. How to reduce the damage to the CNS and promote the reconstruction of the damaged nervous system structure and function recovery has always been the concern of nerve tissue engineering.
Huang L, Wang G.
europepmc +2 more sources
Advances in neuroprotective ingredients of medicinal herbs by using cellular and animal models of Parkinson's disease. [PDF]
Evid Based Complement Alternat Med, 2013 Parkinson’s disease (PD) is a multifactorial disorder, which is neuropathologically identified by age‐dependent neurodegeneration of dopaminergic neurons in the substantia nigra. Development of symptomatic treatments has been partly successful for PD research, but there remain a number of inadequacies in therapeutic strategies for the disease.
More SV +5 more
europepmc +2 more sources
Huang‐Pu‐Tong‐Qiao Formula Ameliorates Tau Phosphorylation by Inhibiting the CaM‐CaMKIV Pathway
Evidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020 Alzheimer’s disease (AD) is a complex neurodegenerative disease. It is a chronic, lethal disease in which brain function is severely impaired and neuronal damage is irreversible. Huang‐Pu‐Tong‐Qiao (HPTQ), a formula from traditional Chinese medicine, has been used in the clinical treatment of AD for many years, with remarkable effects.
Shu Ye +10 more
wiley +1 more source
Tenuigenin Attenuates α‐Synuclein‐Induced Cytotoxicity by Down‐Regulating Polo‐Like Kinase 3 [PDF]
CNS Neuroscience & Therapeutics, 2013 SummaryBackground and aimsTenuigenin (Ten) is a Chinese herbal extract with antioxidative and antiinflammatory effects on toxin‐induced cell models of Parkinson's disease (PD); however, its effects on α‐synuclein toxicity‐based PD models remain unknown.
Jin-Xia, Zhou +15 more
openaire +2 more sources