Results 21 to 30 of about 4,796 (231)

ENHANCED ANTI-TUMOR ACTIVITY OF CD19.CAR-NK CELLS BY INCORPORATING IL-27

Hematology, Transfusion and Cell Therapy, 2023
Autologous T-cells expressing Chimeric Antigen Receptor (CAR) have shown great efficacy against hematologic malignancies, however, severe side effects limit their clinical use.
AFB Biggi, RN Silvestre, JTC Azevedo, MC Tirapelle, KCR Malmegrim, ML Figueiredo, DT Covas, V Picanço-Castro   +7 more
doaj   +1 more source

The role of bone marrow mononuclear cell-conditioned medium in the proliferation and migration of human dermal fibroblasts

Cellular & Molecular Biology Letters, 2017
Background Several recent studies have demonstrated the great potential of bone marrow cells in regenerative medicine, not only for their ability to differentiate to match a damaged cell type, but also because they synthesize and release various growth ...
Yolanda Menéndez-Menéndez, Jesús Otero-Hernández, Jose Antonio Vega, Marcos Pérez-Basterrechea, Silvia Pérez-López, María Álvarez-Viejo, Amaia Ferrero-Gutiérrez   +6 more
doaj   +1 more source

Terapia celular: novos conceitos - novas perspectivas [PDF]

Revista Brasileira de Cardiologia Invasiva, 2008
sao dramaticas, pois contra-dizem o conceito basico de ausencia de atividade mi-totica em orgaos terminalmente diferenciados, como ocoracao e o sistema nervoso central. Consequentemente,observamos uma revolucao cientifica, em que pesqui-sadores estudam as interacoes celulares responsaveispela manutencao da homeostasia em orgaos especiali-zados, como o ...
Perin, Emerson C., Fernandes, Marlos R., Silva, Guilherme V.   +2 more
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ANÁLISE DOS RESULTADOS OBTIDOS COM O USO DO PLERIXAFOR PARA O RESGASTE DAS MOBILIZAÇÕES NO TRANSPLANTE DE CÉLULAS PROGENITORAS HEMATOPOIÉTICAS (CPHS) AUTÓLOGO

Hematology, Transfusion and Cell Therapy
Introdução: Para o transplante autólogo, a fonte de escolha para a coleta de CPHs é o sangue periférico mobilizado. A mobilização acontece através da administração do fator estimulador de colônias de granulócitos (G-CSF) por 4 dias consecutivos.
MP Santos, CHC Ribeiro, PDC Machado, DR Vidal, JPR Azevedo   +4 more
doaj   +1 more source

Both CD133 Cells and Monocytes Provide Significant Improvement for Hindlimb Ischemia, Although They do not Transdifferentiate Into Endothelial Cells

Cell Transplantation, 2010
To address a number of questions regarding the experimental use of bone marrow (BM) stem cells in hindlimb ischemia, including which is the best cell type (e.g., purified hematopoietic stem cell or monocytes), the best route of delivery [intramuscular ...
Fermin M. Sanchez-Guijo M.D., PhD., Enrique Oterino, Maria-Victoria Barbado, Soraya Carrancio, Natalia Lopez-Holgado, Sandra Muntion, Pilar Hernandez-Campo, Luis-Ignacio Sanchez-Abarca, Jose A. Perez-Simon, Jesús F. San Miguel, Jesús G. Briñon, Maria-Consuelo Del Cañizo   +11 more
doaj   +1 more source

Establishment of a simple and efficient platform for car-t cell generation and expansion: from lentiviral production to in vivo studies

Hematology, Transfusion and Cell Therapy, 2020
Introduction: Adoptive transfer of T cells expressing a CD19-specific chimeric antigen receptor (CAR) has shown impressive response rates for the treatment of CD19 + B-cell malignancies in numerous clinical trials. The CAR molecule, which recognizes cell-
Virgínia Picanço-Castro, Pablo Diego Moço, Amanda Mizukami, Leticia Delfini Vaz, Marcelo de Souza Fernandes Pereira, Renata Nacasaki Silvestre, Júlia Teixeira Cottas de Azevedo, Aline de Sousa Bomfim, Mario Soares de Abreu Neto, Kelen Cristina Ribeiro Malmegrim, Kamilla Swiech, Dimas Tadeu Covas   +11 more
doaj   +1 more source

Targeting the Immune System With Mesenchymal Stromal Cell-Derived Extracellular Vesicles: What Is the Cargo's Mechanism of Action?

Frontiers in Bioengineering and Biotechnology, 2019
The potent immunomodulatory activities displayed by mesenchymal stromal cells (MSCs) have motivated their application in hundreds of clinical trials to date.
Jorge Diego Martin-Rufino, Jorge Diego Martin-Rufino, Natalia Espinosa-Lara, Lika Osugui, Fermin Sanchez-Guijo, Fermin Sanchez-Guijo, Fermin Sanchez-Guijo   +6 more
doaj   +1 more source

The Brazilian association of hematology, hemotherapy, and cell therapy (ABHH) and its absolute commitment to ethics and absence of conflicts of interest [PDF]

Hematology, Transfusion and Cell Therapy
Carmino Antonio de Souza, Eduardo Magalhães Rego, Glaciano Nogueira Ribeiro, Silvia Maria Meira Magalhães, Celso Arrais Rodrigues da Silva, Leny Nascimento da Motta Passos, Dimas Tadeu Covas, Renato Sampaio Tavares, Vania T.de Moraes Hungria, Edvan de Queiroz Crusoé, José Francisco Comenalli Marques, Jr, Carlos Sérgio Chiattone, Dante Langhi, Junior, Jorge Vaz Pinto Neto, Violete Petitto Laforga, Angelo Maiolino   +15 more
doaj   +2 more sources

EXPERIÊNCIA DE UM SERVIÇO DE IMUNO-HEMATOLOGIA NA RESOLUÇÃO DE UM CASO COMPLEXO COM ANTICORPOS ANTI-HY E ANTI- JOA

Hematology, Transfusion and Cell Therapy
Introdução: Os serviços de imuno-hematologia enfrentam diariamente desafios na identificação de anticorpos irregulares, sobretudo se envolve anticorpos contra antígenos de alta frequência.
GL Oliveira, EJ Sekiya, ALD Santos, CRCS Kugler, EM Silva, IGV Seco, JCS Pimentel, RA Cardoso, MCAV Conrado, A Alves   +9 more
doaj   +1 more source

A era da terapia celular [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2005
Ate recentemente, a terapia com celulas-tronco hemo-poeticas (CTH) era restrita ao tratamento de doencas hema-tologicas, onco-hematologicas e a pacientes graves comdoencas hereditarias e auto-imunes sem opcoes de cura.Com os novos conhecimentos sobre a plasticidade dasCTH e de experimentos que comprovaram a transdiferenciacaoe a desdiferenciacao ...
openaire   +3 more sources