Results 31 to 40 of about 4,253 (175)

EXPERIÊNCIA DE UM SERVIÇO DE IMUNO-HEMATOLOGIA NA RESOLUÇÃO DE UM CASO COMPLEXO COM ANTICORPOS ANTI-HY E ANTI- JOA

Hematology, Transfusion and Cell Therapy
Introdução: Os serviços de imuno-hematologia enfrentam diariamente desafios na identificação de anticorpos irregulares, sobretudo se envolve anticorpos contra antígenos de alta frequência.
GL Oliveira, EJ Sekiya, ALD Santos, CRCS Kugler, EM Silva, IGV Seco, JCS Pimentel, RA Cardoso, MCAV Conrado, A Alves   +9 more
doaj   +1 more source

Topology‐Encoded Charge Polarity Governs Multiphase Organization in Intrinsically Disordered Protein Polymer Condensates

Small, EarlyView.
Electrostatic topology is shown to program phase separation and internal organization in thermoresponsive intrinsically disordered protein polymer (IDPP) condensates. By comparing oppositely charged IDPPs with a covalent diblock, chain connectivity is revealed to control charge compensation, dense‐phase micropolarity, miscibility, and apparent acid ...
Julio Fernández‐Fernández, Vicente Domínguez‐Arca, Raúl Escribano, Sheila Lorenzo, Sergio Ferrero, Sergio Acosta, José Carlos Rodríguez‐Cabello   +6 more
wiley   +1 more source

Clinical Translation of Mesenchymal Stromal Cell Therapy for Graft Versus Host Disease

Frontiers in Cell and Developmental Biology, 2019
Graft versus host disease (GVHD) is a common condition in patients subjected to allogeneic hematopoietic stem cell transplantation (HSCT). The immune cells derived from the grafted stem cells attack recipient’s tissues, including those from the skin ...
Juliana A. P. Godoy, Raquel M. A. Paiva, Aline M. Souza, Andrea T. Kondo, Jose M. Kutner, Oswaldo K. Okamoto, Oswaldo K. Okamoto   +6 more
doaj   +1 more source

Third Allogeneic Stem Cell Transplantation in Children: A Multicenter Analysis From the Spanish GETH‐TC Pediatric Group

European Journal of Haematology, EarlyView.
ABSTRACT Third allogeneic hematopoietic stem cell transplantation (HSCT3) is rarely performed in pediatric patients and is associated with high toxicity and mortality. Data on outcomes in this setting remain scarce. We conducted a retrospective multicenter study within the Spanish GETH‐TC Pediatric group including 29 children and adolescents who ...
Luisa Sisinni, Sara Vinagre Enríquez, Marta Villalon Herrera, Mercedes Plaza Fornieles, Iván López Torija, Andrea Urtasun Erburu, Laura Alonso García, Alexandra Regueiro García, Maria Trabazo del Castillo, Eduardo J. Bardón‐Cancho, Odelaisy León‐Triana, Carla Miñarro Chacón, José Luís Fuster Soler, Antonio Pérez‐Martínez, Pascual Balsalobre López, Marta Gonzalez‐Vicent, Cristina Díaz de Heredia, on behalf of the GETH‐TC Pediatric Working Group   +17 more
wiley   +1 more source

REAÇÕES ADVERSAS DURANTE COLETA DE CÉLULAS MONONUCLARES EM SERVIÇO DE HEMOTERAPIA DO RIO DE JANEIRO

Hematology, Transfusion and Cell Therapy
Objetivos: Descrever as reações adversas associadas a coletas de células mononucleares encontradas, a fim de monitorar o perfil de intercorrências no serviço de hemoterapia e planejar intervenções precoces, mitigando riscos.
DR Vidal, MAP Cardoso, MM Gramatico, JPR Azevedo, TL Ogassawara, DO Mussi, LM Silva   +6 more
doaj   +1 more source

Human olfactory mesenchymal stromal cells co-expressing horizontal basal and ensheathing cell proteins in culture

Biomédica: revista del Instituto Nacional de Salud, 2020
Introduction: The olfactory neuro-epithelium has an intrinsic capability of renewal during lifetime provided by the existence of globose and horizontal olfactory precursor cells.
Carlos Ayala-Grosso, Rosalinda Pieruzzini, Leslie Vargas-Saturno, José E. Cardier   +3 more
doaj   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, Volume 28, Issue 14, 22 July 2026.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

Advanced Materials Technologies, Volume 11, Issue 14, 22 July 2026.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto, Manuel Alejandro Vazquez Valle, Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Iván Velasco, Genaro Vázquez‐Victorio, Itzel Escobedo‐Avila   +6 more
wiley   +1 more source

Terapia celular nas doenças oftalmológicas [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2009
Avancos no campo das celulas-tronco proporcionaram muita perspectiva para uso destas celulas na regeneracao dos tecidos oculares danificados por doencas as quais nao possuem tratamento disponivel ate o momento. Terapia baseada com celulas-tronco para regeneracao e reparo ocular constitui uma esperanca para a restauracao da funcao visual em individuos ...
openaire   +3 more sources

Multiple myeloma: A tale of deregulated transcription factors

HemaSphere, Volume 10, Issue 7, July 2026.
Abstract A comprehensive understanding of the molecular mechanisms underlying multiple myeloma (MM) pathogenesis is essential for developing therapeutic strategies that overcome disease heterogeneity and treatment relapse. In this review, we focus on transcription factors (TFs), key regulators of gene expression that play critical roles in normal ...
Nahia Gómez‐Echarte, Edurne San José‐Enériz, Estíbaliz Urizar‐Compains, Paula Rodriguez‐Otero, Felipe Prósper, Xabier Agirre   +5 more
wiley   +1 more source