Results 21 to 30 of about 4,553 (135)

Both CD133 Cells and Monocytes Provide Significant Improvement for Hindlimb Ischemia, Although They do not Transdifferentiate Into Endothelial Cells

Cell Transplantation, 2010
To address a number of questions regarding the experimental use of bone marrow (BM) stem cells in hindlimb ischemia, including which is the best cell type (e.g., purified hematopoietic stem cell or monocytes), the best route of delivery [intramuscular ...
Fermin M. Sanchez-Guijo M.D., PhD., Enrique Oterino, Maria-Victoria Barbado, Soraya Carrancio, Natalia Lopez-Holgado, Sandra Muntion, Pilar Hernandez-Campo, Luis-Ignacio Sanchez-Abarca, Jose A. Perez-Simon, Jesús F. San Miguel, Jesús G. Briñon, Maria-Consuelo Del Cañizo   +11 more
doaj   +1 more source

Establishment of a simple and efficient platform for car-t cell generation and expansion: from lentiviral production to in vivo studies

Hematology, Transfusion and Cell Therapy, 2020
Introduction: Adoptive transfer of T cells expressing a CD19-specific chimeric antigen receptor (CAR) has shown impressive response rates for the treatment of CD19 + B-cell malignancies in numerous clinical trials. The CAR molecule, which recognizes cell-
Virgínia Picanço-Castro, Pablo Diego Moço, Amanda Mizukami, Leticia Delfini Vaz, Marcelo de Souza Fernandes Pereira, Renata Nacasaki Silvestre, Júlia Teixeira Cottas de Azevedo, Aline de Sousa Bomfim, Mario Soares de Abreu Neto, Kelen Cristina Ribeiro Malmegrim, Kamilla Swiech, Dimas Tadeu Covas   +11 more
doaj   +1 more source

EXPERIÊNCIA DE UM SERVIÇO DE IMUNO-HEMATOLOGIA NA RESOLUÇÃO DE UM CASO COMPLEXO COM ANTICORPOS ANTI-HY E ANTI- JOA

Hematology, Transfusion and Cell Therapy
Introdução: Os serviços de imuno-hematologia enfrentam diariamente desafios na identificação de anticorpos irregulares, sobretudo se envolve anticorpos contra antígenos de alta frequência.
GL Oliveira, EJ Sekiya, ALD Santos, CRCS Kugler, EM Silva, IGV Seco, JCS Pimentel, RA Cardoso, MCAV Conrado, A Alves   +9 more
doaj   +1 more source

Targeting the Immune System With Mesenchymal Stromal Cell-Derived Extracellular Vesicles: What Is the Cargo's Mechanism of Action?

Frontiers in Bioengineering and Biotechnology, 2019
The potent immunomodulatory activities displayed by mesenchymal stromal cells (MSCs) have motivated their application in hundreds of clinical trials to date.
Jorge Diego Martin-Rufino, Jorge Diego Martin-Rufino, Natalia Espinosa-Lara, Lika Osugui, Fermin Sanchez-Guijo, Fermin Sanchez-Guijo, Fermin Sanchez-Guijo   +6 more
doaj   +1 more source

Efficacy and safety of frail patients treated with ciltacabtagene autoleucel in the real world: A Center for International Blood and Marrow Transplant Research analysis

Cancer, Volume 132, Issue 19, 1 October 2026.
Abstract Background Ciltacabtagene autoleucel (cilta‐cel), an anti–B‐cell maturation antigen (BCMA) chimeric antigen receptor T‐cell (CAR‐T) therapy, is approved for relapsed/refractory multiple myeloma (RRMM). Methods Using the Center for International Blood and Marrow Transplant Research registry, this study evaluated outcomes of frail patients ...
Hira Mian, Muhammad Salman Faisal, Tiening Chen, Ruta Brazauskas, Temitope Oloyede, Nausheen Ahmed, Aimaz Afrough, Larry D. Anderson, Rahul Banerjee, Jesus Berdeja, Aram Bidikian, Jakob Devos, Binod Dhakal, Ajoy Dias, Danai Dima, Yvonne A. Efebera, Lohith Gowda, Doris K. Hansen, Hamza Hashmi, Heather J. Landau, Lazaros Lekakis, Abu‐Sayeef Mirza, Ravi Narra, Krina Patel, Ashley E. Rosko, Mark Schroeder, Surbhi Sidana, Saad Usmani, Marcelo C. Pasquini, Taiga Nishihori, Othman Salim Akhtar, Meera Mohan   +31 more
wiley   +1 more source

Third Allogeneic Stem Cell Transplantation in Children: A Multicenter Analysis From the Spanish GETH‐TC Pediatric Group

European Journal of Haematology, Volume 117, Issue 4, Page 943-952, October 2026.
ABSTRACT Third allogeneic hematopoietic stem cell transplantation (HSCT3) is rarely performed in pediatric patients and is associated with high toxicity and mortality. Data on outcomes in this setting remain scarce. We conducted a retrospective multicenter study within the Spanish GETH‐TC Pediatric group including 29 children and adolescents who ...
Luisa Sisinni, Sara Vinagre Enríquez, Marta Villalon Herrera, Mercedes Plaza Fornieles, Iván López Torija, Andrea Urtasun Erburu, Laura Alonso García, Alexandra Regueiro García, Maria Trabazo del Castillo, Eduardo J. Bardón‐Cancho, Odelaisy León‐Triana, Carla Miñarro Chacón, José Luís Fuster Soler, Antonio Pérez‐Martínez, Pascual Balsalobre López, Marta Gonzalez‐Vicent, Cristina Díaz de Heredia, on behalf of the GETH‐TC Pediatric Working Group   +17 more
wiley   +1 more source

REAÇÕES ADVERSAS DURANTE COLETA DE CÉLULAS MONONUCLARES EM SERVIÇO DE HEMOTERAPIA DO RIO DE JANEIRO

Hematology, Transfusion and Cell Therapy
Objetivos: Descrever as reações adversas associadas a coletas de células mononucleares encontradas, a fim de monitorar o perfil de intercorrências no serviço de hemoterapia e planejar intervenções precoces, mitigando riscos.
DR Vidal, MAP Cardoso, MM Gramatico, JPR Azevedo, TL Ogassawara, DO Mussi, LM Silva   +6 more
doaj   +1 more source

Clinical Translation of Mesenchymal Stromal Cell Therapy for Graft Versus Host Disease

Frontiers in Cell and Developmental Biology, 2019
Graft versus host disease (GVHD) is a common condition in patients subjected to allogeneic hematopoietic stem cell transplantation (HSCT). The immune cells derived from the grafted stem cells attack recipient’s tissues, including those from the skin ...
Juliana A. P. Godoy, Raquel M. A. Paiva, Aline M. Souza, Andrea T. Kondo, Jose M. Kutner, Oswaldo K. Okamoto, Oswaldo K. Okamoto   +6 more
doaj   +1 more source

Patterned ELR‐Gelatin Hydrogels Enable Rapid Endothelial Monolayer Formation via Bioactive Matrix Chemistry and Surface Topography

Advanced Healthcare Materials, Volume 15, Issue 34, 11 September 2026.
Micro‐ and nano‐patterned elastin‐like recombinamer (ELR) hydrogels integrate bioactive matrix chemistry with defined surface topography. The combined cues promote rapid endothelial cell capture, alignment, and monolayer formation on soft substrates.
Jagoda Litowczenko, Yannick Richter, Martyna Michalska, Piotr Paczos, Karine Tadevosyan, Daniel Uribe, Jose Carlos Rodriguez‐Cabello, Ioannis Papakonstantinou, Angel Raya   +8 more
wiley   +1 more source

Human olfactory mesenchymal stromal cells co-expressing horizontal basal and ensheathing cell proteins in culture

Biomédica: revista del Instituto Nacional de Salud, 2020
Introduction: The olfactory neuro-epithelium has an intrinsic capability of renewal during lifetime provided by the existence of globose and horizontal olfactory precursor cells.
Carlos Ayala-Grosso, Rosalinda Pieruzzini, Leslie Vargas-Saturno, José E. Cardier   +3 more
doaj   +1 more source