Monoclonal antibodies against human astrocytomas and their reactivity pattern [PDF]
, 1987 The establishment of hybridomas after fusion of X63-Ag8.653 mouse myeloma cells and splenocytes from mice hyperimmunized against human astrocytomas is presented. The animals were primed with 5 × 106 chemically modified uncultured or cultured glioma cells.
B. Martin +36 more
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CCN2/CTGF silencing blocks cell aggregation in embryonal carcinoma P19 cell
Brazilian Journal of Medical and Biological Research, 2011 Connective tissue growth factor (CCN2/CTGF) is a matricellular-secreted protein involved in extracellular matrix remodeling. The P19 cell line is an embryonic carcinoma line widely used as a cellular model for differentiation and migration studies.
D.P. Aguiar +2 more
doaj +2 more sources
Case Reports in Oncology, 2012 Somatic malignancy arising from presacral or retroperitoneal primary teratoma is extremely rare. We report the case of a 37-year-old male patient with adenocarcinoma of respiratory type arising from primary presacral teratoma, but which first presented ...
S.P. Ho +3 more
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Increased expression of 5-hydroxytryptamine(2A/B) receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention [PDF]
, 2010 Background Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and limited responsiveness to available treatments. It is characterised by epithelial cell injury, fibroblast activation and proliferation and extracellular matrix deposition ...
Amarie, Oana Veronica +8 more
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Human teratocarcinoma cell lines. A review [PDF]
International Journal of Andrology, 1981 A review is given of studies on human teratocarcinoma cell lines in culture. A human ovarian teratocarcinoma line (PA‐1) has been characterized in detail (Zeuthen et al. 1980) and has been shown to exhibit some properties of human teratocarcinoma stem‐cells.
openaire +2 more sources
Isolation and characterization of an inhibitory human monoclonal antibody specific to the urokinase-type plasminogen activator, uPA [PDF]
, 2017 The serine protease urokinase (uPA, urokinase-type plasminogen activator) is over-expressed in certain tumors and is considered to be the strongest single indicator of poor prognosis in patients with metastatic breast cancer. In this article, we describe
Neri, Dario +3 more
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Mammalian myosin I alpha, I beta, and I gamma: new widely expressed genes of the myosin I family. [PDF]
, 1993 A polymerase chain reaction strategy was devised to identify new members of the mammalian myosin I family of actin-based motors. Using cellular RNA from mouse granular neurons and PC12 cells, we have cloned and sequenced three 1.2-kb polymerase chain ...
Greene, LA, Joyce, MP, Sherr, EH
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Partnership of PGC-1α and HNF4α in the regulation of lipoprotein metabolism [PDF]
, 2006 Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) is a transcriptional coactivator involved in several aspects of energy metabolism. It is induced or activated under different stimuli in a highly tissue-specific manner and subsequently
Cooper, M. +8 more
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The Effects of Taurine on hNT Neurons Transplanted in Adult Rat Striatum
Cell Transplantation, 2000 Taurine acts as an antioxidant able to protect neurons from free radical-mediated cellular damage. Moreover, it modulates the immune response of astrocytes that participate in neurodegenerative processes.
Selva Rivas-Arancibia +5 more
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Megalin in normal tissues and carcinoma cells carries oligo/poly α2,8 deaminoneuraminic acid as a unique posttranslational modification [PDF]
, 2018 In rat kidney, megalin, a member of the low density lipoprotein receptor gene family, is the sole glycoprotein which carries oligo/poly α2,8 deaminoneuraminic acid (KDN) as a posttranslational modification. We have investigated immunoprecipitated megalin
Meier, Mirjam +2 more
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