Results 11 to 20 of about 26,590 (258)

Isotretinoin; A review on the Utilization Pattern in Pregnancy [PDF]

Advanced Pharmaceutical Bulletin, 2018
Purpose: Isotretinoin is the most effective anti-acne drug with a long-term remission. However; it contains severe teratogenic effects with serious adverse drug reactions, which limits the use of medication.
Sajad Khiali, Afshin Gharekhani, Taher Entezari-Maleki   +2 more
doaj   +1 more source

Teratogenic Effects of Antiepileptic Drugs

Pediatric Neurology Briefs, 1997
Data from 5 prospective European studies totaling 1,221 children exposed to antiepileptic drugs (AED) during pregnancy and 158 children of unexposed control pregnancies were analyzed to quantify the risk of major congenital malformations (MCM) and are ...
J Gordon Millichap
doaj   +1 more source

Teratogenic effect of 1.3 bis (p-Hydroxyphenyl)urea on Wistar rats (Rattus norvegicus L.) [PDF]

Pharmacia
Pain is a physiological disorder that pregnant women often experience, so they take various medications to relieve the pain. Many pain relievers on the market have teratogenic effects on pregnant women. 1.3 bis(p-Hydroxyphenyl)urea is a modification of p-
Denny Satria, Ziza Putri Aisyia Fauzi, Urip Harahap, Yuandani, Syukur Berkat Waruwu, Hari Purnomo   +5 more
doaj   +3 more sources

PREEXISTING MATERNAL DISORDERS – RISK FACTORS FOR NEWBORN CONGENITAL ANOMALIES [PDF]

Romanian Journal of Pediatrics, 2016
Congenital anomalies may be determined by genetic or environmental factors or a combination of the two factors. Maternal disease can affect fetal development through specific effects of metabolic products or maternal antibody transfer.
Elena Braha, Alina Costina Luca
doaj   +1 more source

Teratogenic Effects of Methylazoxymethanol

Experimental Biology and Medicine, 1967
SummaryMethylazoxymethanol (MAM), the aglycone of cycasin, a naturally occurring glucoside of cycad plants, causes retardation of growth and a variety of malformations in embryos of the golden hamster. This same substance was previously shown to be carcinogenic, hepatotoxic and to cause mutations, methylation of nucleic acids and chromosome breakage.
M, Spatz, W J, Dougherty, D W, Smith
openaire   +2 more sources

Pregnancy in epileptic patients: comparison between well-established therapeutic strategies and opportunities coming from new drugs

Clinical Management Issues, 2013
Treating women affected by epilepsy during pregnancy is challenging.  Clinicians have to consider both the teratogenic effects of Antiepileptic Drugs (AEDs) and the risk of seizure recurrence.
Francesca Pizzo, Arianna Dilaghi, Anna Maria Romoli, Silvia Pradella, Andrea La Licata, Barbara Chiocchetti, Alessandra Pistelli, Marco Paganini   +7 more
doaj   +1 more source

Teratogenic of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (TCDD) on Eye Diameters and Body Weight in Chicken Embryo

Jurnal Medik Veteriner, 2021
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a chemical compound resulting from the burning effect that is very dangerous for humans, plants, or animals which can cause skin damage, immunotoxic, hepatotoxic, carcinogenic, teratogenic, effects on ...
Muhammad Aviv Firdaus, Herlina Pratiwi, Ani Setianingrum, Gegana Wimaldy Airlangga   +3 more
doaj   +1 more source

Breast Cancer Case using Tamoxifen during Pregnancy: A Case Report and Literature Review

Sudan Journal of Medical Sciences, 2017
This is a case of 32 years old nulliparous female who was diagnosed in November 2004 as a case of carcinoma of the right breast, luminal A, (Estrogen Receptor positive Progesterone receptor negative, Her 2 negative, Ki67 10 %), poorly differentiated ...
Kamal Eldein H. Mohamed, Sarah Mirghani
doaj   +1 more source

Structure-Activity Relationship (SAR) Model for Predicting Teratogenic Risk of Antiseizure Medications in Pregnancy by Using Support Vector Machine

Frontiers in Pharmacology, 2022
Teratogenicity is one of the main concerns in clinical medications of pregnant women. Prescription of antiseizure medications (ASMs) in women with epilepsy during pregnancy may cause teratogenic effects on the fetus.
Liyuan Kang, Yifei Duan, Cheng Chen, Shihai Li, Menglong Li, Lei Chen, Zhining Wen, Zhining Wen   +7 more
doaj   +1 more source

Reduction in mortality and teratogenicity following simultaneous administration of folic acid and vitamin E with antiepileptic, antihypertensive and anti-allergic drugs

Journal of Pharmacy and Bioallied Sciences, 2014
Aim: The present study was designed to evaluate the teratogenic effects on breeding pattern in mice following administration of lamotrigine (LT) and levetiracetam (LV) and its combination with anti-hypertensive and anti-allergic drugs.
Shahana Wahid, Rafeeq Alam Khan, Zeeshan Feroz   +2 more
doaj   +1 more source