Results 171 to 180 of about 7,092 (271)

Multimodal optical imaging for the assessment of the teratogenic effects of ethanol on zebrafish development. [PDF]

J Biomed Opt
Lewis LA, Karim MM, Zevallos-Delgado C, Nia MB, Empie SM, Alwis HHHN, Singh M, Aglyamov S, Lekven AC, Mayerich D, Larin KV.   +10 more
europepmc   +1 more source

Sodium sulfite can reliably induce chemical hypoxia without toxic effects in the model sea anemone species, Exaiptasia diaphana

Limnology and Oceanography: Methods, Volume 24, Issue 10, October 2026.
Abstract Climate change is accelerating the deoxygenation of aquatic ecosystems, so understanding its effects on biological processes is increasingly critical. An emerging method for inducing hypoxia during experimentation utilizes sodium sulfite (SSI) to scavenge oxygen; however, it remains unclear if hypoxia‐inducing concentrations of SSI are toxic ...
Zhen Qin, Lorenzo Vassura, Bianca A. Parodi, Elise M. J. Laetz   +3 more
wiley   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

Investigation of Teratogenic Concerns in the Coronavirus Disease of 2019 Era. [PDF]

Birth Defects Res
Richardson K, Daykin EC, Shields K, Hashmi SS, Harris-Sagaribay L, Daniels M, Ashfaq M.   +6 more
europepmc   +1 more source

Current Animal Models of Cleft Lip and/or Palate: A Narrative Review. [PDF]

Biomedicines
Chang IW, Zheng S, Zheng Z, Le AD, Chung CH, Laird MF, Li C.   +6 more
europepmc   +1 more source

Preclinical and Toxicology Studies of LPM7100328, a Novel Oral GnRH Antagonist

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT LPM7100328 is a novel oral GnRH antagonist being developed for the prevention of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation. The studies presented herein reported assessment of safety in favor of human clinical trials.
Yao Wang, Junxian Zhao, Fangxia Zou, Wanglin Jiang, Jianzhao Zhang, Pengfei Yu, Liang Ye, Xiaolin Sun, Chunmei Li, Jingwei Tian   +9 more
wiley   +1 more source

The aetiology distribution of birth defects based on the China Birth Cohort Study. [PDF]

BMJ Paediatr Open
Liu X, Liu R, Wang C, Yan R, Gao S, Su S, Nie X, Su J, Zhang E, Xie S, Liu J, Zhang Y, Yue W, Peng X, Yin C.   +14 more
europepmc   +1 more source

DEET‐cyclodextrin inclusion complexes for mosquito and tick repellency: Extended repellency time and no zebrafish embryotoxicity

Pest Management Science, Volume 82, Issue 10, Page 9653-9665, October 2026.
Hydroxypropyl‐β‐cyclodextrin (HPβCD)–N,N‐diethyl‐meta‐toluamide (DEET) complex extended tick repellency to 168 h. Full protection against Aedes aegypti for 7 h with HPβCD‐DEET. HPβCD reduced DEET release and skin retention significantly. No embryotoxicity observed below 325 mg L−1 in zebrafish model.
Gessyka Rayana Silva Pereira, Gleidson Cardoso, Maria Luiza Kuhn Camargo, Michele Resende Machado, Mayara Macedo Barrozo, Juscelino Rodrigues, Gisele Augusto Rodrigues de Oliveira, Caio Monteiro, Christian Luz, Ricardo Neves Marreto, Stephânia Fleury Taveira   +10 more
wiley   +1 more source

Identification and cheracterization of Cripto antagonists to improve the use of stem cell-based therapy in neurodegenerative disorders [PDF]

, 2008
Lonardo, Enza
core   +1 more source

Medication decision making under uncertainty: Considering chronic disease and pregnancy potential. [PDF]

Semin Perinatol
Birru Talabi M, Miller R, Krishnamurti T.   +2 more
europepmc   +1 more source