Results 171 to 180 of about 6,483 (296)

Paternal use of metformin and risk of major congenital malformations: A meta‐analysis of 4 studies

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1940-1943, June 2026.
Abstract Metformin is the first‐line drug for the treatment of Type 2 diabetes. In 2022, a Danish registry‐based study reported a 40% increased risk of major congenital malformations following paternal exposure during spermatogenesis. This raised widespread concern about the use of metformin in males of reproductive age.
Per Damkier, Marleen M. H. J. van Gelder, Krista F. Huybrechts, Lin‐Chieh Meng, Sonia Hernandez‐Diaz, Jan Nielsen, Bente M. Nørgård, Hedvig Nordeng   +7 more
wiley   +1 more source

Teratogens

, 1996
John F. Jackson
core   +1 more source

Human stem cell-based embryo models: innovation, ethics, and policy. [PDF]

Hum Reprod
Arias AM, Rivron N, Tajbakhsh S, Johnston J, Alev C, Bally-Cuif L, Böke E, Cavazza T, Cave E, Cyranoski D, David L, Esteban MA, Fu J, Geijsen N, de Graeff N, Hanna JH, Hopwood N, Inamdar MS, Lanner F, Leeners B, Liu Z, Jean Leon M, Minchiotti G, Moris N, Munsie M, Niakan KK, Pourquie O, Pasque V, Pera M, Peng Y, Petropoulos S, Ramanathan S, Rossant J, Rugg-Gunn P, Saitou M, Sermon K, Silva J, Theunissen T, Turco M, Wallingford J, Wang H, Warmflash A, Wu J, Yu L.   +43 more
europepmc   +1 more source

Teratogens

, 1987
Tomas Pexieder
core   +1 more source

Morphometric-Assisted Prediction of Developmental Toxicity Using Stem Cell-Based Embryo Models in Microwells. [PDF]

Adv Healthc Mater
Shankar V, Pappa AZ, van Blitterswijk C, Vrij E, Giselbrecht S.   +4 more
europepmc   +1 more source

Vascular Mechanisms in the Etiology of Hemifacial Microsomia: A Systematic Review of Epidemiological, Clinical, and Genetic Evidence

Birth Defects Research, Volume 118, Issue 6, June 2026.
ABSTRACT Background Hemifacial microsomia (HFM) is a congenital craniofacial malformation characterized by unilateral hypoplasia of structures derived from the first and second pharyngeal arches. Although the phenotype is well described, the underlying etiology remains incompletely understood.
Karl Jacobs, Aarya Baramakeh, Hedwig van der Meer, Hans Korfage, Bernadette de Bakker, Geerling Langenbach, Roelof Jan Oostra, Frank Lobbezoo   +7 more
wiley   +1 more source

Experiences of sexual and reproductive health screening and counseling in the clinical setting among adolescents and young adults with rheumatic disease. [PDF]

Pediatr Rheumatol Online J
Huynh B, Ott MA, Tarvin SE.
europepmc   +1 more source

Hydranencephaly in Neonate With Prenatal Exposure to Alcohol During Pregnancy

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Hydranencephaly (HE) is a rare congenital condition characterized by near‐total absence of the cerebral hemispheres, replaced by cerebrospinal fluid, most commonly resulting from in utero bilateral internal carotid artery occlusion; although maternal alcohol consumption is associated with fetal neurodevelopmental abnormalities, its direct role
Dibya Raj Chaudhary, Diwakar Koirala, Samiksha Lamichhane, Bivek Mishra   +3 more
wiley   +1 more source

Facial Clefts and the Trigeminal Nerve: A Narrative Review of the Literature and Clinical Considerations in the Era of Personalized Medicine. [PDF]

J Pers Med
Lucangeli N, Cannistrà MS, Scopelliti D, Parisi P, Tripodi D, Barbet P, Cannistrà C.   +6 more
europepmc   +1 more source

Limitations of FAERS‐based analyses of paternal drug exposure: The critical need for maternal data integration

Andrology, Volume 14, Issue 5, Page 1079-1080, July 2026.
Mikako Goto, Izumi Fujioka, Yasuha Ogawa, Sachi Koinuma, Koushi Yamaguchi   +4 more
wiley   +1 more source