Results 151 to 160 of about 6,483 (296)

Transfer of paracetamol across the placenta and fetal blood–brain barriers and its safety for use in pregnancy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley   +1 more source

Risk and Benefit of Drug Use During Pregnancy

open access: yesInternational Journal of Medical Sciences, 2005
Environmental teratogenic factors (e.g. alcohol) are preventable. We focus our analysis on human teratogenic drugs which are not used frequently during pregnancy. The previous human teratogenic studies had serious methodological problems, e.g.
doaj  

Chemical-induced heart defects using a transgenic zebrafish model. [PDF]

open access: yesToxicol Sci
Liu S   +6 more
europepmc   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

open access: yesChirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz   +1 more
wiley   +1 more source

Synthesizing polyethersulphone membranes with hybrid iron/nickel nanoparticles for dyes removal: An efficient biogenesis approach

open access: yesThe Canadian Journal of Chemical Engineering, Volume 104, Issue 7, Page 3593-3617, July 2026.
Abstract Industrial wastewater contamination by azo dyes poses a significant environmental challenge. This study reports the green synthesis of bimetallic iron/nickel (Fe/Ni) nanoparticles using moringa leaf extract, which acted as both a reducing and capping agent, and their incorporation into polyethersulphone (PES) membranes to produce eco‐friendly ...
Qusay A. Almajras   +7 more
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

open access: yesAngewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Airway Involvement in Conradi–Hünermann–Happle Syndrome: A Novel Clinical Manifestation

open access: yesThe Laryngoscope, Volume 136, Issue 7, Page 3240-3245, July 2026.
We report the first documented case of airway involvement in Conradi–Hünermann–Happle syndrome (CDPX2), an X‐linked dominant form of chondrodysplasia punctata caused by pathogenic variants in EBP. A 2‐month‐old female with genetically confirmed CDPX2 developed severe subglottic stenosis and persistent respiratory distress requiring CPAP; cross ...
Enrique G. Villarreal   +3 more
wiley   +1 more source

Society for Maternal‐Fetal Medicine Statement: Acetaminophen use during pregnancy

open access: yesPregnancy, Volume 2, Issue 4, July 2026.
Abstract Acetaminophen has long been considered safe to use during pregnancy. A growing body of cohort studies and meta‐analyses has explored the potential association between prenatal acetaminophen use and neurodevelopmental outcomes in children. Although some studies report modestly increased risks of neurodevelopmental disorders in children exposed ...
Society for Maternal‐Fetal Medicine (SMFM)   +1 more
wiley   +1 more source

Prenatal Prescription Opioid Analgesic Exposure and Academic Performance in Third Grade Children: A Population‐Based Cohort Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 8, Page 1658-1670, July 2026.
ABSTRACT Objective To evaluate the association between prenatal exposure to opioids analgesics and academic performance in third grade children. Design Population‐based cohort study using linked data from New South Wales birth records, medicine dispensing data, and national standardised test results.
Bianca Varney   +7 more
wiley   +1 more source

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