Results 141 to 150 of about 11,254 (283)
Abstract Autosomal polycystic kidney disease (ADPKD) is the most common form of inherited kidney disease. The international guideline developer, Kidney Disease: Improving Global Outcomes (KDIGO), published a 2025 clinical practice guideline reflecting advances in genetic testing and the first disease‐modifying agent, tolvaptan.
Mia E. Abdy +26 more
wiley +1 more source
French guidelines on systemic treatments for moderate‐to‐severe psoriasis in adults: Update 2025
New 2025 French guidelines update psoriasis management with revised algorithms integrating recent systemic therapies. They recommend methotrexate, adalimumab or ustekinumab as first‐line treatments and provide guidance for special psoriasis forms, comorbidities, pregnancy and long‐term management.
Marie Masson Regnault +51 more
wiley +1 more source
A Barrier to Understanding Teratogenicity: The Critical Periods of Sensitivity for Most Structural Birth Defects Precede the Established Hemochorial Placenta. [PDF]
Nangle MA, Shah K, Kumar S, Lipinski RJ.
europepmc +1 more source
Update of the EuroGuiDerm evidence‐based guideline for the treatment of acne—Short version
The 2025 EuroGuiDerm guideline update provides evidence‐based recommendations for acne management, addressing systemic antibiotics, systemic isotretinoin, hormonal therapies including spironolactone and contraceptives, and new topical agents. Key considerations include treatment duration, safety, pregnancy‐specific guidance and minimizing antibiotic ...
Alexander Nast +22 more
wiley +1 more source
FATE-MAP predicts teratogenicity and human gastrulation failure modes by integrating deep learning and mechanistic modeling. [PDF]
Rufo J +8 more
europepmc +1 more source
Abstract Reports of teratogenic embryos in elasmobranchs have been documented in multiple species, with proposed aetiologies including environmental disturbances, genetic mutations, predation, exposure to endocrine‐disrupting compounds and maternal stress.
Douglas de Castro Ribeiro +2 more
wiley +1 more source
Chemical-induced heart defects using a transgenic zebrafish model. [PDF]
Liu S +6 more
europepmc +1 more source
We review the characteristic changes to the limb soft tissue and neurovascular abnormalities that have been described in the congenital limb birth defect, Radial Dysplasia. These include consistent changes in muscle anatomy or absence of specific muscles, persistent median arteries and absent radial arteries and consistent alterations in neural ...
Marco Correia Duarte +6 more
wiley +1 more source

