Results 121 to 130 of about 7,092 (271)
Modulation of sebocyte function in acne: A pathway‐inclusive review
Journal of the European Academy of Dermatology and Venereology, EarlyView.Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis +3 more
wiley +1 more source
Journal of Anatomy, EarlyView.The chicken embryo is an accessible, low‐cost and genetically tractable model for studying limb development and congenital limb differences. We directly compared chicken and human limb musculature using published evidence alongside our own data and observations.
Julia Dong Hwa Oh +4 more
wiley +1 more source
Journal of Anatomy, EarlyView.The XenCart Protocol provides a reproducible way to visualize and quantify how the developing craniofacial skeleton responds to experimental perturbation. Embryos are exposed to defined conditions, craniofacial cartilage is stained with Alcian blue, imaged, and analyzed morphometrically.
Umar Aziz +4 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Pregnancy requires the coordinated maternal reorganization of lipid and endocrine pathways to sustain fetal growth and anticipate neonatal nutrition. Leptin, produced by adipose tissue and the placenta, acts as an integrative signal linking maternal energy status with trophoblast function and vascular adaptation, while cholesterol provides ...
Julio Flores +4 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend New approach methodologies (NAMs) to test the pharmaco‐ and chemicokinetics of compound transfer across the human placental barrier in late pregnancy. Abstract This review addresses an important and timely topic at the intersection of placental biology with respect to barrier transfer kinetics, toxicology and mathematical ...
Paul Brownbill, Eleanor Doman
wiley +1 more source
Clinico-Radiologic Perspective of a Case of Hemifacial Microsomia [PDF]
Journal of Clinical and Diagnostic Research, 2016 Mandakini Subhash Mandale +3 more
doaj +1 more source
Psychotropic medication and the fetal brain
The Journal of Physiology, EarlyView.Abstract figure legend Brain region changes linked to in‐utero psychotropic exposure. Abstract Medications known to cross the blood–brain barrier (psychotropic medications) are commonly prescribed to women during pregnancy, often for the management of mental illness.
Oliver Gale‐Grant, Tomoki Arichi
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida +7 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley +1 more source