Results 101 to 110 of about 11,254 (283)

Alternative Developmental Toxicity Screening Methods Using Chick Embryo‐Based Models

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Jeong Hwan Kim, Cheoljin Park, Donghee Kim, Wonjun Jeong, Jinsoo Lee   +4 more
wiley   +1 more source

Cutis Marmorata Telangiectatica Congenita in a Preterm Female Newborn: Case Report and Review of the Literature

La Pediatria Medica e Chirurgica, 2014
Cutis Marmorata Telangiectatica Congenita (CMTC) is a rare, sporadic condition usually present at birth characterized by localized or generalized persistent cutis marmorata, telangiectasia and phlebectasia.
C. De Maio, G. Pomero, A. Delogu, E. Briatore, M. Bertero, P. Gancia   +5 more
doaj   +1 more source

A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts. [PDF]

, 2016
Next-generation sequencing (NGS) can identify and validate new biomarkers of cancer onset, progression and therapy resistance. Substantial archives of formalin-fixed, paraffin-embedded (FFPE) cancer samples from patients represent a rich resource for ...
Adamian, Yvess, Bouvet, Michael, Brown, Mark, Chang, Alexander, Doebler, Robert, Fleming, Jason, Gharibi, Armen, Hoffman, Robert M, Hoover, Malachia, Katz, Matthew H, Kelber, Jonathan A, Lee, Jacqueline, Maawy, Ali   +12 more
core   +2 more sources

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos, Iosifina Gounaki, Spyros Dokianakis, Georgios Gkotsis, Maria‐Christina Nika, Eleni Aleiferi, Athanasios S Stasinakis, Nikos Katsarakis, Nikolaos S Thomaidis, Thrassyvoulos Manios, Michalis S Fountoulakis, Danae Venieri   +11 more
wiley   +1 more source

Possible Effects of Immunosuppressive Therapy on Male Fertility and Pregnancy Outcomes After Paternal Exposure in Kidney Transplant Patients

Bezmiâlem Science
Kidney transplantation is a crucial treatment for improving the quality of life of patients with renal failure. Immunosuppressive drugs are necessary to prevent organ rejection and are vital for the success of the transplantation.
Ersan HOROZ, İsmail YILMAZ, Yusuf Özlem İLBEY   +2 more
doaj   +1 more source

Review on the Toxicity and Safety of Medicinal Plants during Pregnancy

Proceedings
Introduction: Although herbs are widely used and considered safe, they can be toxic, especially during pregnancy [...]
Aniket Rajesing Girase, Javesh Kashinath Patil, Devshree Yashwantbhai Patel, Harsha Vasudev Chaudhari, Sachinkumar Madhukar Mahajan   +4 more
doaj   +1 more source

Current considerations on the teratogens and their effects during pregnancy

Medisan, 2022
Introduction: The development reached by teratology as science and the clinical observations made by the scientists,  allowed to establish their principles, represented by a series of factors that determine the capacity of an agent to cause congenital ...
Sandra Yiset Calzadilla Lara, Aylén Uriarte Nápoles, Farah María Ricardo Saint Félix, Cecilia Melian Savigñón   +3 more
doaj  

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

JCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf, Sarjit Singh, Jill P. Pell, Scott M. Nelson, Daniel F. Mackay, Michael Fleming   +5 more
wiley   +1 more source

Managing Skin Diseases During Pregnancy: Treatment Discontinuation, Concerns and Physician Counselling

JEADV Clinical Practice, EarlyView.
Physiological changes during pregnancy can trigger or worsen dermatological conditions, yet evidence‐based guidance for safe management remains limited. In a cross‐sectional survey of 273 pregnant women, 33.7% reported having a skin disease, and 56% experienced worsening of symptoms.
Frederikke Seeberg, Anne Sofie Frølunde, Mette Deleuran, Line Kolding, Christian Vestergaard   +4 more
wiley   +1 more source

Knee arthroplasty failure is associated with significant systemic multimetal exposure

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study investigated whether patients scheduled for revision total knee arthroplasty (TKA) are systemically exposed to arthroplasty metals, and whether systemic metal levels in these patients differ depending on the implants' levels of constraint.
Anna Flindt, Katrin Huesker, Georg Volk, Juliane Fuchs, André Hofer, Ulrich Schietsch, Georgi I. Wassilew, Janosch Schoon, Anastasia Rakow   +8 more
wiley   +1 more source