Results 81 to 90 of about 6,483 (296)

Small head circumference at birth: an 8-year retrospective cohort study in China

BMJ Paediatrics Open, 2019
Objective Head circumference is considered a reliable assessment of the volume of the underlying brain. We sought to identify risk factors (maternal factors or antenatal antecedents) for microcephaly and to assess the effects of microcephaly on neonatal ...
Wen Sun, Nathalie Auger, Shiliang Liu, Yanmei Pan, Lijuan Dai, Sihui Li, Sushan Xie, Shi Wu Wen, Dunjin Chen   +8 more
doaj   +1 more source

Predicting seizure freedom in the postpartum period: Findings from the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs study

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate whether seizure freedom in pregnancy predicts seizure freedom in the postpartum period in women with epilepsy (WWE). Prior studies have shown that seizure freedom prior to conception strongly predicts seizure freedom during pregnancy.
Emma C. Osterhaus, Wesley T. Kerr, Kimford J. Meador, Jacqueline A. French, Angela K. Birnbaum, P. Emanuela Voinescu, Elizabeth Gerard, Page B. Pennell   +7 more
wiley   +1 more source

SARS-CoV-2 pseudoparticles preferentially infect ectoderm in human embryonic tissues

Frontiers in Cell and Developmental Biology
IntroductionThe early stages of human embryonic development are challenging to study in pregnant women.MethodsA “disease-in-a-dish” model was utilized to investigate SARS-CoV-2 infection of human embryonic stem cells and the three germ layers (ectoderm ...
Ann Song, Ann Song, Prue Talbot
doaj   +1 more source

From abortion-inducing medications to Zika Virus Syndrome: 27 years experience of the First Teratogen Information Service in Latin America

Genetics and Molecular Biology, 2019
In 1990, the first Teratogen Information Service in Brazil (SIAT) was implemented in the Medical Genetics Service at Hospital de Clinicas de Porto Alegre.
Lavinia Schüler-Faccini, Maria Teresa Vieira Sanseverino, Alberto Mantovani Abeche, Fernanda Sales Luiz Vianna, Lucas Rosa Fraga, Anastacia Guimaraes Rocha, André Anjos da Silva, Paulo Ricardo Assis de Souza, Artur Hartmann Hilgert, Camila Pocharski Barbosa, Caroline Grasso Kauppinem, Daniela Fernandes Martins, Daniela Silva Santos, Gabriel Henrique Colpes, Gabriela Ecco, Helena Margot Flores Soares da Silva, Louise Piva Penteado, Tatiane dos Santos   +17 more
doaj   +1 more source

A translational multimodal machine‐learning prototype predicting valproate response in epilepsy treatment

Epilepsia, EarlyView.
Abstract Objective Epilepsy affects ~1% of the global population and often requires lifelong antiseizure medication (ASM) therapy. Valproic acid (VPA) is a commonly prescribed first‐line ASM, yet only approximately half of patients achieve sustained seizure freedom. Treatment selection remains largely empirical.
Simeon Platte, Afsheen Kumar, Giorgia Guerini, Massimo Pandolfo, Denise Haslinger, Colin B. Josephson, Guillermo Delgado‐García, Navprabhjot Kaur, Michaela‐Pauline Lux, Heiko Stempfle, Chantal Depondt, Reetta Kälviäinen, Felix Rosenow, Sophie von Brauchitsch, Karl Martin Klein, Andreas G. Chiocchetti   +15 more
wiley   +1 more source

Education and Labor Market Consequences of Teenage Childbearing: Evidence Using the Timing of Pregnancy Outcomes and Community Fixed Effects [PDF]

The question of whether giving birth as a teenager has negative economic consequences for the mother remains controversial despite substantial research. In this paper, we build upon existing literature, especially the literature that uses the experience ...
Barbara L. Wolfe, Jason M. Fletcher
core   +2 more sources

Timing of conception after methotrexate and subsequent pregnancy outcomes: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Methotrexate is widely used to treat ectopic pregnancy (EP). Concerns about its teratogenicity have led to uncertainty regarding the optimal interval before attempting conception. Guidelines recommend a 3‐month washout period, while the manufacturer advises 6 months. Evidence on the safety of early conception is limited.
Bar Rosh, Joul Hadad, Naomi Gronich
wiley   +1 more source

Evaluation of the knowledge and practices of pregnant Yemeni Women regarding teratogens

, 2017
Purpose: To investigate the knowledge and practice of pregnant women with regards to teratogens.Methods: A month-long cross-sectional study was carried out among 150 pregnant women selected from four Motherhood and Child Healthcare Centers (MCHCs) in ...
Ba-Samad, Suad M., Anaam, Mohammed Saif, Bajubair, Mahmoud Salem, Sales, Ibrahim, Alfadly, Saeed O., Mancy, Wael H., Wajid, Syed, Alarifi, Mohammed N., Abdulghani, Mahfoudh Al-Musali M., Babelghaith, Salmeen D.   +9 more
core   +1 more source

TERATOGENIC PROPERTIES OF DRUGS. BACKGROUND INFORMATION

Педиатрическая фармакология, 2013
The article presents the most significant steps in the development of ideas about drugs’ effects on fetus. It features the thalidomide tragedy and features of thalidomide teratogenic properties, as well as data on thalidomide syndrome prevention ...
A. A. Ivanova, A. V. Mikhailov, A. S. Kolbin   +2 more
doaj   +1 more source

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui, Adrian Florea, Leila Tekaya   +2 more
wiley   +1 more source