Results 71 to 80 of about 6,107 (224)

Pharmacotherapy for Cirrhosis in Japan

open access: yesPortal Hypertension &Cirrhosis, Volume 4, Issue 2, Page 111-119, June 2025.
As cirrhosis progresses from the compensated to the decompensated stage, liver disease‐related events such as varices, ascites, encephalopathy, sarcopenia, jaundice, and bleeding tendency, as well as liver carcinogenesis, can occur at a high rate. With the advent of new pharmacotherapies for cirrhosis in the last decade, liver fibrosis has been shown ...
Hiroki Nishikawa, Soo Ki Kim, Akira Asai
wiley   +1 more source

Incidence and type of adverse events in patients with cirrhosis receiving terlipressin: A systematic review and meta-analysis

open access: yesHepatology Communications
Background: Terlipressin has been widely used for various cirrhosis-related complications, but its safety profile remains controversial. Herein, this issue was systematically evaluated.
Yiyang Shang   +6 more
semanticscholar   +1 more source

Pregnancy Outcomes in Women With Liver Cirrhosis: A National Prospective Cohort Study Using the UK Obstetric Surveillance System

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue 7, Page 935-943, June 2025.
ABSTRACT Objective Describe maternal/fetal outcomes of pregnant women with cirrhosis. Design Prospective, national cohort study utilising the UK Obstetric Surveillance System between 1st June 2017 and 30th November 2020. Setting UK. Population Pregnant women with cirrhosis.
Melanie Nana   +7 more
wiley   +1 more source

Comparison of Open Albumin Dialysis (OPAL) With Prometheus Fractionated Plasma Separation and Adsorption (FPSA) and Standard Medical Treatment for Acute‐On‐Chronic Liver Failure

open access: yesArtificial Organs, Volume 49, Issue 6, Page 997-1011, June 2025.
The retrospective cohort study is the first to compare OPAL with Prometheus and hemodialysis for adult ACLF patients. Both extracorporeal liver support systems were comparably effective with regard to the reduction of bilirubin and creatinine levels surpassing the effects seen in hemodialysis. We recognized improvements in clinical scoring, such as the
Justa Friebus‐Kardash   +8 more
wiley   +1 more source

Involvement of the ADAMTS13–von Willebrand factor axis in acute kidney injury in mice with liver cirrhosis

open access: yesHepatology Research, Volume 55, Issue 6, Page 844-858, June 2025.
Abstract Aim Hepatorenal syndrome‐induced acute kidney injury (AKI) comprises AKI and liver cirrhosis (LC) and is a risk factor for poor prognoses of patients with LC. Decreased a disintegrin‐like metalloproteinase with thrombospondin type 1 motif 13 (ADAMTS13) activity and increased von Willebrand factor (vWF) antigen levels are associated with LC ...
Masayoshi Takami   +9 more
wiley   +1 more source

Association of Anaesthetists guidelines: the use of blood components and their alternatives

open access: yesAnaesthesia, Volume 80, Issue 4, Page 425-447, April 2025.
Summary Background The administration of blood components and their alternatives can be lifesaving. Anaemia, bleeding and transfusion are all associated with poor peri‐operative outcomes. Considerable changes in the approaches to optimal use of blood components and their alternatives, driven by the findings of large randomised controlled trials and ...
Akshay Shah   +12 more
wiley   +1 more source

Early Dynamics of Portal Pressure Gradient After TIPS Insertion Predict Mortality

open access: yesAlimentary Pharmacology &Therapeutics, Volume 61, Issue 7, Page 1175-1182, April 2025.
The lack of increase in portal pressure gradients (PPG) within 24 h after TIPS implantation is associated with poorer outcomes. ABSTRACT Background Transjugular intrahepatic portosystemic shunt (TIPS) placement leads to a reduction in portal pressure and an improvement in survival in patients with recurrent and refractory ascites and variceal ...
P. A. Reuken   +14 more
wiley   +1 more source

A comparison of vasopressin, terlipressin, and lactated ringers for resuscitation of uncontrolled hemorrhagic shock in an animal model.

open access: yesPLoS ONE, 2014
AimThe aim of this study is to compare the effect of lactated ringer (LR), vasopressin (Vaso) or terlipressin (Terli) on uncontrolled hemorrhagic shock (UHS) in rats.Methods48 rats were divided into four treatment groups for UHS study.
Chien-Chang Lee   +7 more
doaj   +1 more source

RATIONAL FOR CONTINUING TERLIPRESSIN AFTER ENDOSCOPIC VARICEAL LIGATION IN ACUTE VARICEAL HAEMORRHAGE NEEDS FURTHER EVIDENCE: A PILOT STUDY [PDF]

open access: diamond, 2022
Ram C. Poudel   +5 more
openalex   +1 more source

Controversies in terlipressin and transplantation in the United States: How do we MELD the two?

open access: yesLiver transplantation
Hepatorenal syndrome-acute kidney injury (HRS-AKI) is a severe complication of cirrhosis that carries a poor prognosis. The recent Food and Drug Administration approval of terlipressin has substantial implications for managing HRS-AKI and liver ...
E. Przybyszewski   +10 more
semanticscholar   +1 more source

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