Results 51 to 60 of about 3,810 (184)
Angewandte Chemie, Volume 137, Issue 28, July 7, 2025.Targeting Amyloid‐β (Aβ) aggregation requires a peptide‐based approach that accounts for the structural heterogeneity of Aβ. Here, we employ topological reprogramming via disulfide bonds to stabilize antiparallel β‐sheets within the dimeric peptide.
Dongjoon Im +5 more
wiley +2 more sources
Intraoperative Use of Vasoactive Agents in Non‐Cardiac Surgery: Protocol for a Post Hoc Cohort Study
Acta Anaesthesiologica Scandinavica, Volume 70, Issue 2, February 2026.ABSTRACT Background Intraoperative hypotension is a well‐known clinical condition and often treated with vasoactive agents. Previous cohort studies have indicated that large numbers of patients receive this treatment, but they have been limited to specific surgical populations or single agents.
Emilie Stokholm Bækgaard +6 more
wiley +1 more source
, 2016 Objective To study the differences in mortality between terlipressin and somatostatin treatments in cirrhotic patients with esophageal variceal bleeding (EVB) and renal functional impairment (RFI). Methods The National Health Insurance Database, part of
Hung, Tsung-Hsing; Tsai, Chen-Chi; Tseng, Chih-Wei; Tseng, Kuo-Chih; Hsieh, Yu-Hsi; Tsai, Chih-Chun +6 more
core +1 more source
Short-term vasoactive agent treatment driven by physicians’ preference in acute esophageal variceal bleeding in a tertiary center [PDF]
PeerJ, 2019 Background Vasoactive drugs are frequently used in combination with endoscopic variceal ligation (EVL) in treatment of acute esophageal variceal bleeding (EVB).
Yoen Young Chuah +8 more
doaj +2 more sources
Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.Background In cardiogenic shock (CS), titration of both the choice and dosage of inotropes and vasopressors is crucial. The vasoactive–inotropic score (VIS) quantifies hemodynamic support, while the effect of temporal VIS change on prognosis remains unclear. This study evaluated the association between the vasoactive–inotropic score reduction rate (VRR)
Yi-Le Ning +9 more
wiley +1 more source
Неотложная медицинская помощьAIM OF THE STUDY. Comparative clinical analysis of the efficacy of terlipressin and octreotide as additional drug therapy to mechanical hemostasis with nitinol stent in patients with liver cirrhosis complicated by bleeding from esophageal varices ...
A. Yu. Anisimov, Yu. A. Anisimov
doaj +1 more source
Canadian Journal of Gastroenterology and Hepatology, Volume 2026, Issue 1, 2026.Background Upper gastrointestinal bleeding (UGIB) is a significant cause of cirrhosis decompensation; however, there is still controversy on risk factors for poor outcomes. This study aims to explore the impact of additional variables, such as liver disease etiology and intensive care unit (ICU) accessibility, on mortality, rebleeding, and infection ...
Mariana Barros Marcondes +7 more
wiley +1 more source
Terlipressin-related Ischaemic Necrosis of the Skin: A Rare Complication [PDF]
, 2019 Terlipressin is used for the treatment of bleeding oesophageal varices and hepatorenal syndrome in patients with cirrhosis. Adverse effects are usually minimal.
Novais, António +4 more
core +1 more source
Severe hyponatraemia to terlipressin treatment.
, 2013 Terlipressin is a vasopressin analogue. The clinical effect is attributable to affinity to vasopressin-1a receptors. However, it also has affinity to renal vasopressin-2 receptors, which can lead to water retention and dilutional hyponatraemia. We report
Poulsen, Anja +1 more
core +1 more source
Canadian Journal of Gastroenterology and Hepatology, Volume 2026, Issue 1, 2026.Background Esophageal variceal bleeding (EVB) is a serious complication of cirrhosis and a major cause of upper gastrointestinal hemorrhage, carrying substantial risks of mortality and treatment failure. Prognostic scores are essential for guiding management.
Khoa Phuoc Nguyen +4 more
wiley +1 more source