Results 31 to 40 of about 3,587 (183)

Safety, Tolerability, Pharmacokinetics, and Efficacy of Terlipressin Delivered by Continuous Intravenous Infusion in Patients with Cirrhosis and Refractory Ascites

GastroHep, 2022
Background. Terlipressin is a long acting synthetic analogue of vasopressin, which is used to manage variceal bleeding and hepatorenal syndrome.
Jasmohan S. Bajaj, James H. Fischer, Patrick Yeramian, Edith A. Gavis, Andrew Fagan, Paolo Angeli, Guadalupe Garcia-Tsao, Jonathan M. Adams, Penelope Markham   +8 more
doaj   +1 more source

Terlipressin for the Prevention and Treatment of Renal Decline in Hepatorenal Syndrome: A Drug Profile

Gastroenterology Insights, 2023
Hepatorenal syndrome stands as one of several potential triggers of acute kidney injury in individuals grappling with either acute or persistent liver ailments. The nature of the decline in kidney function has led to the identification of two variants of
Ahlam Ayyad, Rami A. Al-Horani
doaj   +1 more source

Vasoconstrictor Therapy for Acute Kidney Injury Hepatorenal Syndrome: A Meta-Analysis of Randomized Studies

Gastro Hep Advances, 2023
Background and Aims: Type 1 hepatorenal syndrome (HRS) is a rapid deterioration in kidney function in patients with cirrhosis. Data on efficacy of vasoconstrictors for type 1 HRS have shown mixed results.
Ashwani K. Singal, Geralyn Palmer, Lauren Melick, Mohamed Abdallah, Paul Kwo   +4 more
doaj   +1 more source

Is there any role for terlipressin in the extremely low birth weight infant with refractory septic shock?

Journal of Pediatric and Neonatal Individualized Medicine, 2012
Terlipressin, a synthetic long-acting analogue of vasopressin, has been investigated as a second line vasopressor in adults and children with refractory septic shock, i.e.
Francesca Bissolo, Carlo Alberto Forcellini, Stefania Spaggiari, Marcella Gaffuri, Giuseppe Pagano, Paolo Biban   +5 more
doaj   +1 more source

Terlipressin in Hepatorenal Syndrome

, 2011
Objective: To compare the pharmacology, dosing, and adverse reactions of vasopressin and terlipressin for the treatment of hepatorenal syndrome (HRS) and assess the efficacy of the investigational drug terlipressin for HRS.
Tanna B Cooper, Joseph E Mazur, Joseph F Dasta   +2 more
core   +1 more source

Continuous terlipressin infusion is associated with improved diet intake and muscle strength in patients awaiting liver transplant

JHEP Reports, 2019
Background & Aims: Portal hypertension contributes to the pathogenesis of malnutrition and sarcopenia in cirrhosis via multiple mechanisms. Terlipressin is a vasopressin analogue that we administer via continuous outpatient infusion, as a bridge to ...
Brooke Chapman, Paul Gow, Marie Sinclair, Timothy Hanrahan, Peter Angus, Tess McClure, Chris Mills, Ryma Terbah, Adam Testro   +8 more
doaj   +1 more source

Elevated liver regeneration in response to pharmacological reduction of elevated portal venous pressure by terlipressin after partial hepatectomy. [PDF]

, 2014
BACKGROUND Liver regeneration is of crucial importance for patients undergoing living liver transplantations or extended liver resections and can be associated with elevated portal venous pressure, impaired hepatic regeneration, and postoperative ...
Candinas, Daniel, Patsenker, Eleanora, Beldi, Guido, De Gottardi, Andrea, Fahrner, René, Stickel, Felix, Montani, Matteo, Keogh-Stroka, Deborah M.   +7 more
core   +1 more source

Effects of terlipressin infusion during hepatobiliary surgery on systemic and splanchnic haemodynamics, renal function and blood loss: a double-blind, randomized clinical trial

BMC Anesthesiology, 2019
Background Terlipressin, in general, is a vasopressor which acts via V1 receptors. Its infusion elevates mean blood pressure and can reduce bleeding which has a splanchnic origin.
Magdy Mohammed Mahdy, Mostafa Samy Abbas, Emad Zarief Kamel, Mohamed Fathy Mostafa, Ragaa Herdan, Shimaa Abbas Hassan, Ramy Hassan, Ahmed M. Taha, Tameem M. Ibraheem, Bashir A. Fadel, Mohammed Geddawy, Jehan Ahmed Sayed, Osama Ali Ibraheim   +12 more
doaj   +1 more source

Effects of short-term simultaneous infusion of dobutamine and terlipressin in patients with septic shock: The DOBUPRESS study [PDF]

, 2008
Background. Terlipressin bolus infusion may reduce cardiac output and global oxygen supply. The present study was designed to determine whether dobutamine may counterbalance the terlipressin-induced depression in mixed-venous oxygen saturation (Sv(O2 ...
Rehberg, S., Westphal, M., Ertmer, C., Lange, M., Dünser, M., Van Aken, H., Pietropaoli, P., Morelli, A.   +7 more
core   +1 more source

Terlipressin combined with conservative fluid management attenuates hemorrhagic shock-induced acute kidney injury in rats

Scientific Reports, 2022
Hemorrhagic shock (HS), a major cause of trauma-related mortality, is mainly treated by crystalloid fluid administration, typically with lactated Ringer’s (LR).
Leticia Urbano Cardoso Castro, Denise Aya Otsuki, Talita Rojas Sanches, Felipe Lima Souza, Mirela Aparecida Rodrigues Santinho, Cleonice da Silva, Irene de Lourdes Noronha, Amaro Nunes Duarte-Neto, Samirah Abreu Gomes, Luiz-Marcelo Sá Malbouisson, Lucia Andrade   +10 more
doaj   +1 more source