Results 41 to 50 of about 3,587 (183)

Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury

Experimental Physiology, EarlyView.
Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley   +1 more source

Management Strategies for Refractory Esophageal Varices

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Refractory esophageal varices that are difficult to control or unresponsive to endoscopic treatment remain a major clinical challenge in the management of portal hypertension. This review provides a comprehensive overview of treatment strategies for these cases, along with a comparative analysis of the American Association for the Study of ...
Keita Maki, Hiroaki Haga, Yoshiyuki Ueno
wiley   +1 more source

Terlipressin-Related Acute Myocardial Infarction: A Case Report and Literature Review

Kaohsiung Journal of Medical Sciences, 2004
Acute ST-segment elevation myocardial infarction after the administration of terlipressin in patients with hemorrhagic esophageal varices is a rare but life-threatening complication.
Min-Yi Lee, Chin-Sheng Chu, Kun-Tai Lee, Hsiang-Chun Lee, Ho-Ming Su, Kai-Hung Cheng, Sheng-Hsiung Sheu, Wen-Ter Lai   +7 more
doaj   +1 more source

Terlipressin as an adjunct vasopressor in refractory hypotension after tricyclic antidepressant intoxication

, 2006
AIM OF STUDY: To report the management of cardiovascular failure refractory to standard catecholamine therapy with terlipressin in a patient with tricyclic antidepressant (TCA) intoxication. CASE REPORT: A 41-year-old woman, with suicidal ingestion of 11.
Dünser, Martin W, Zuidema, Xander, de Jager, Cornelis P C, Rozendaal, Frans W, Wenzel, Volker   +4 more
core   +1 more source

Cutaneous Ischaemia Following Terlipressin Therapy for Hepatorenal Syndrome [PDF]

Journal of Clinical and Diagnostic Research, 2018
Hepatorenal Syndrome (HRS) is a potentially fatal complication of hepatic failure and portal hypertension. Among the various treatments available including octreotide, midodrine and albumin, the current standard of care for stable patients is ...
Aneesh Basheer, Dayanandan Yoganandan, Meera Baby John, Prem Kumar Guna   +3 more
doaj   +1 more source

Plasma Adsorption Perfusion (BR‐350) Versus Open Albumin Dialysis (OPAL) for Hyperbilirubinemia in Hepatic Failure in Cirrhotic Patients

Artificial Organs, Volume 50, Issue 4, Page 610-624, April 2026.
The therapy with PAP using BR‐350 resulted in a significant decrease of bilirubin concentrations. The median relative reduction of bilirubin was comparable between PAP and OPAL (47% vs. 40%, p = 0.29). The crossover comparison between the single session of PAP using BR‐350 and OPAL revealed similar relative reduction rates of bilirubin.
Justa Friebus‐Kardash, Alica Ochs, Amina Louzi, Andreas Kribben, Bartosz Tyczynski, Jassin Rashidi‐Alavijeh, Andreas Schütte, Hartmut H. Schmidt, Amos Zeller   +8 more
wiley   +1 more source

Terlipressin for hepatorenal syndrome

, 2012
Clinical trials suggest that terlipressin improves renal function in hepatorenal syndrome, but the evidence concerning mortality is ...
Kurt Christensen, Christensen, Kurt, Aleksander Krag, Gluud, Lise Lotte, Lise Lotte Gluud, Erik Christensen, Christensen, Erik, Krag, Aleksander   +7 more
core   +1 more source

Antiparallel β‐Sheet as a Key Motif of Amyloid‐β Inhibitor Designed via Topological Peptide Reprogramming

Angewandte Chemie, Volume 137, Issue 28, July 7, 2025.
Targeting Amyloid‐β (Aβ) aggregation requires a peptide‐based approach that accounts for the structural heterogeneity of Aβ. Here, we employ topological reprogramming via disulfide bonds to stabilize antiparallel β‐sheets within the dimeric peptide.
Dongjoon Im, Ye Eun Lee, Gyusub Yoon, William A. Goddard III, Tae Su Choi, Hugh I. Kim   +5 more
wiley   +2 more sources

Intraoperative Use of Vasoactive Agents in Non‐Cardiac Surgery: Protocol for a Post Hoc Cohort Study

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 2, February 2026.
ABSTRACT Background Intraoperative hypotension is a well‐known clinical condition and often treated with vasoactive agents. Previous cohort studies have indicated that large numbers of patients receive this treatment, but they have been limited to specific surgical populations or single agents.
Emilie Stokholm Bækgaard, Morten Vester‐Andersen, Anders Granholm, Morten Hylander Møller, Ben Creagh‐Brown, Ib Jammer, Mette Krag   +6 more
wiley   +1 more source

The current applications and future directions of terlipressin. [PDF]

Hepatol Commun
Terlipressin is a vasopressin analog with potent splanchnic vasoconstrictor properties. It has an established role in managing portal hypertensive bleeding and hepatorenal syndrome-acute kidney injury, with a growing body of evidence demonstrating ...
Liu D, Testro A, Majumdar A, Sinclair M.
europepmc   +2 more sources