Results 91 to 100 of about 21,600,368 (295)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Short-Term and Long-Term Travel Time Prediction Using Transformer-Based Techniques

open access: yesApplied Sciences
In the evolving field of Intelligent Transportation Systems (ITSs), accurate and reliable traffic prediction is essential in enhancing management and planning capabilities.
Hui-Ting Christine Lin   +2 more
doaj   +1 more source

Time preferences for the very long term

open access: yesActa Psychologica, 2001
Many important decisions concern outcomes delayed by decades or centuries. Whereas some economists have argued that inter-generational discount rates should be lower than intra-generational rates, three experiments found that inter- and intra-generational discount rates were quite similar.
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

On the Incomparability of Cache Algorithms in Terms of Timing Leakage

open access: yesLogical Methods in Computer Science, 2019
Modern computer architectures rely on caches to reduce the latency gap between the CPU and main memory. While indispensable for performance, caches pose a serious threat to security because they leak information about memory access patterns of programs via execution time.
Pablo Cañones, Boris Köpf, Jan Reineke
openaire   +6 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Oscillation for a Nonlinear Dynamic System with a Forced Term on Time Scales

open access: yesAbstract and Applied Analysis, 2014
We consider a class of two-dimensional nonlinear dynamic system with a forced term on a time scale 𝕋 and obtain sufficient conditions for all solutions of the system to be oscillatory.
Xinli Zhang, Shanliang Zhu
doaj   +1 more source

Effect of alpha and gamma binaural beats on reaction time and short-term memory

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2018
Background: Binaural beats, a kind of cortical entrainment, are an auditory illusion that occurs when two sinusoidal waves at slightly different frequencies are presented separately to each ear. Binaural beats influence behavior and cognition through the
Lavanya Shekar   +2 more
doaj   +1 more source

MOZAIC Time-Term Analysis [PDF]

open access: yesGeophysical Journal International, 1976
Summary The time-term approach to the interpretation of refraction travel-time data is extended to deal with observation systems which are not, at first sight, suitable for time-term analysis. This so-called MOZAIC method is based on the premise that there exist areas of equal delay time to any refractor and that the distribution of such areas can ...
openaire   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

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