Results 111 to 120 of about 3,848,281 (310)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Long Term Time-Lapse Imaging of Geographic Atrophy: A Pilot Study. [PDF]

Front Med (Lausanne), 2022
Paques M, Norberg N, Chaumette C, Sennlaub F, Rossi E, Borella Y, Grieve K.   +6 more
europepmc   +1 more source

Review of: "Unpacking the Complexities of Bitcoin Volatility: A Time Series Data with Long-term Memory or Long-range Dependence" [PDF]

, 2023
Juan Gabriel Brida
openalex   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Long-term time trends in reactivated herpes simplex infections and treatment in Sweden. [PDF]

BMC Infect Dis, 2022
Lopatko Lindman K, Lockman-Lundgren J, Weidung B, Olsson J, Elgh F, Lövheim H.   +5 more
europepmc   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Development of a long-term time-weighted exposure metric that accounts for missing data in the Seychelles Child Development Study. [PDF]

Neurotoxicology, 2022
Thurston SW, Harrington D, Mruzek DW, Shamlaye C, Myers GJ, van Wijngaarden E.   +5 more
europepmc   +1 more source

Assessment of long-term structural movements in a historic cliffside construction through Lomb-Scargle spectral analysis of unevenly spaced time records: the Punta Begoña Galleries (Getxo, Spain) [PDF]

, 2022
Jesús A. Uriarte, R. Morales‐Juberias, Jon Ander Clemente, Iñaki Antigüedad, Tomás Morales   +4 more
openalex   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Purifying Selection Determines the Short-Term Time Dependency of Evolutionary Rates in SARS-CoV-2 and pH1N1 Influenza. [PDF]

Mol Biol Evol, 2022
Ghafari M, du Plessis L, Raghwani J, Bhatt S, Xu B, Pybus OG, Katzourakis A.   +6 more
europepmc   +1 more source