Results 121 to 130 of about 21,600,368 (295)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

xLSTMTime: Long-Term Time Series Forecasting with xLSTM

open access: yesAI
In recent years, transformer-based models have gained prominence in multivariate long-term time series forecasting (LTSF), demonstrating significant advancements despite facing challenges such as high computational demands, difficulty in capturing ...
Musleh Alharthi, Ausif Mahmood
doaj   +1 more source

Long Term Time-Lapse Imaging of Geographic Atrophy: A Pilot Study. [PDF]

open access: yesFront Med (Lausanne), 2022
Paques M   +6 more
europepmc   +1 more source

Yield curve, time varying term premia, and business cycle fluctuations [PDF]

open access: yes
Using data for U.S. and Canada, we find evidence of the time-varying nature of risk premia, which are obtained as difference between long term interest rates and their expected values. We then apply Kalman filtering to extract the conditional variance of
Modena, Matteo
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The time validity of Philip's two‐term infiltration equation: An elusive theoretical quantity?

open access: yesVadose Zone Journal
The two‐term infiltration equation I(t)=St+At is commonly used to determine the sorptivity, S (LT−1/2), and product, A=cKs (LT−1), of the dimensionless multiple c and saturated soil hydraulic conductivity Ks (LT−1) from cumulative vertical infiltration ...
Jasper A. Vrugt   +5 more
doaj   +1 more source

Short-Term Forecasting of Non-Stationary Time Series

open access: yesEngineering Proceedings
Forecasting climate events is crucial for mitigating and managing risks related to climate change; however, the problem of non-stationarity in time series (NTS) arises, making it difficult to capture and model the underlying trends.
Amir Aieb   +3 more
doaj   +1 more source

Long-term time trends in reactivated herpes simplex infections and treatment in Sweden. [PDF]

open access: yesBMC Infect Dis, 2022
Lopatko Lindman K   +5 more
europepmc   +1 more source

Economics of long-term care in Ohio

open access: yes, 1992
Electronic data (1 file : 445123 bytes).; "Ohio Long-Term Care Research Project"--Cover.; Includes bibliographical references (p.
Mehdizadeh, Shahla A.   +1 more
core  

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