Results 141 to 150 of about 3,461,095 (294)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

LarvaSPA, A Method for Mounting Drosophila Larva for Long-Term Time-Lapse Imaging. [PDF]

J Vis Exp, 2020
Ji H, Han C.
europepmc   +1 more source

Long-term observation of cardiac function in Duchenne's muscular dystrophy. Evaluation using systolic time intervals and echocardiography.

, 1990
Toshinori Utsunomiya, Hideki Mori, Noritoshi Shibuya, Y Oku, Shuzo Matsuo, Kunitake Hashiba   +5 more
openalex   +2 more sources

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

An Immobilization Technique for Long-Term Time-Lapse Imaging of Explanted <i>Drosophila</i> Tissues. [PDF]

Front Cell Dev Biol, 2020
Bostock MP, Prasad AR, Chaouni R, Yuen AC, Sousa-Nunes R, Amoyel M, Fernandes VM.   +6 more
europepmc   +1 more source

Modeling long‐term persistence in hydroclimatic time series using a hidden state Markov Model [PDF]

, 2000
Mark Thyer, George Kuczera
openalex   +1 more source

Optimum-apportionment of each word's presentation time based upon time-continuous model of short-term memory.

, 1993
Hirokazu Yokoi
openalex   +2 more sources

Is it time to change the term negative symptoms?

European Neuropsychopharmacology, 2022
Emilio Fernandez-Egea, Noham Wolpe
openaire   +2 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Time-Varying Volatility and the Dynamic Behavior of the Term Structure

, 1991
Robert Engle, Victor Ng
openalex   +1 more source