Results 91 to 100 of about 6,010,689 (339)

Do Hospital Visit Restrictions Cause Increase in the Doses of Morphine in Terminal Care? Spiritual Pain and Palliative Care in the COVID-19 Pandemic. [PDF]

open access: yesAm J Med, 2022
Kudo H   +12 more
europepmc   +1 more source

Philosophical Reflection about Death and End-of-Life Experiences in Medical Education: A Brief Report of Medical Students' Experiences in a Flipped Classroom [PDF]

open access: yesInterdisciplinary Journal of Virtual Learning in Medical Sciences
Death and end-of-life care are crucial yet often overlooked topics in healthcare education. This study explores the integration of philosophical reflection into a Flipped Classroom (FC) model within a graduate course on Collective Health at Universidade ...
Carolina Marquez   +2 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

The relationship between the perception of spiritual care and attitudes and behaviors toward end-of-life care in critical care nurses in northern Turkey [PDF]

open access: yesJournal of Research Development in Nursing and Midwifery
Background: Critical care nurses’ spiritual care and end-of-life care practices are important in providing and maintaining holistic care. This study aimed to explore the relationship between critical care nurses’ perceptions of spiritual care and their ...
Asuman Çobanoğlu
doaj  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Overview of Systematic Reviews on Factors Related to the Structure and Functioning of Residential Long-Term Care Facilities for Older Adults

open access: yesGeriatrics
Objective: To identify factors influencing the structure and functioning of long-term residential care facilities for older adults worldwide, in order to uncover practices and support evidence-based improvements in care delivery.
Aurélio Matos Andrade   +5 more
doaj   +1 more source

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