Results 181 to 190 of about 725,409 (217)

Protective effects of hemoglobin vesicles on intestinal ischemia-reperfusion injury in a rat model of thoracic aortic occlusion. [PDF]

JVS Vasc Sci
Tsuruta K, Fukushima H, Sakai H.
europepmc   +1 more source

A Novel Gelatin Hydrogel‐Based Drug‐Delivery System Promotes Antimicrobial Efficacy in a Pyogenic Spondylodiscitis Rat Model

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT Background Spondylodiscitis/spondylitis is an intractable disease requiring long‐term intravenous antibiotics administration. However, drug delivery is greatly restricted because of the avascular nature in the intervertebral disc, which not only delays recovery but increases antimicrobial resistance and osteomyelitis. The purpose of this study
Kunihiko Miyazaki, Yutaro Kanda, Takashi Yurube, Yoshiki Takeoka, Takeru Tsujimoto, Hiroki Ohnishi, Tomoya Matsuo, Masao Ryu, Naotoshi Kumagai, Kohei Kuroshima, Yoshiaki Hiranaka, Yasuhiko Tabata, Ryosuke Kuroda, Kenichiro Kakutani   +13 more
wiley   +1 more source

Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane

Molecular Carcinogenesis, Volume 65, Issue 9, Page 1052-1062, September 2026.
ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh, Eun‐Ryeong Hahm, Bruce L. Jacobs, Shivendra V. Singh   +3 more
wiley   +1 more source

Exosomal miR-181d-5p derived from distal airway stem cells inhibit apoptosis of pulmonary vascular endothelial cells in COPD mice by targeting PDAP1. [PDF]

Stem Cell Res Ther
Song Q, Liu C, Lin L, Zhou A, Li T, Zhang P, Zeng Y, Chen P.   +7 more
europepmc   +1 more source

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

MedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait, Anna Cargnoni, Franco Scaldaferri, Loris Lopetuso, Antonietta Rosa Silini, Ornella Parolini   +5 more
wiley   +1 more source

HIF1α Attenuates Doxorubicin-Induced Cardiotoxicity by Activating TEX264-Associated ER-phagy. [PDF]

J Am Heart Assoc
Wang X, Zhan G, Li J, Yang X, Wen Y, Tang Y, Zhang P, Xia Y, Yang X.   +8 more
europepmc   +1 more source

Immunoglobulin Kappa Light Chain Produced by Cardiomyocytes and Participates in Maintaining Intercalated Disc Integrity

MedComm, Volume 7, Issue 9, September 2026.
This study identifies Igκ expression in cardiomyocytes, with predominant localization at ICDs. Cardiomyocyte‐specific Igκ knockout induces cardiac dysfunction and ICDs structural disorganization. Mechanistically, Igκ stabilizes plectin to facilitate desmin‒actin network assembly and anchor desmin to DSP, which is critical for maintaining ICDs ...
Zhu Zhu, Yixuan Sheng, Yun Chang, Yuan Chang, Miaomiao Xu, Wenjing Zhou, Wenxiu Wang, Qingyuan Liao, Zhan Shi, Meng Zhang, Feng Lan, Jiangping Song, Xiaoyan Qiu   +12 more
wiley   +1 more source

Comparison of three commercial sperm freezing media with regard to the influence on sperm motility, vitality and DNA fragmentation. [PDF]

Transl Androl Urol
Kruschel EL, Steinert S, Godlewska MA, Hahn G, Laubis K, Blenck NL, Salzbrunn A, Soave A, Schneider SW, von Kopylow K.   +9 more
europepmc   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

Sperm DNA fragmentation and its impact on pregnancy outcomes: a narrative review focusing on threshold definition and clinical strategies. [PDF]

Transl Androl Urol
Cheng S, Yuan Y, Wang Z, Xie Z, Chen Q, Liu Z, Chen Y, Song T, Yan M, Zheng Z, Lin H.   +10 more
europepmc   +1 more source