Results 91 to 100 of about 15,760,783 (334)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Quasilinearization method for causal terminal value problems involving Riemann-Liouville fractional derivatives

Electronic Journal of Differential Equations, 2019
In this work, we construct new definitions for a causal terminal value problem involving Riemann-Liouville fractional derivatives, and study the unique solution by combining techniques from generalized quasilinearization.
Coskun Yakar, Mehmet Arslan
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Optimal dividends problem with a terminal value for spectrally positive Levy processes [PDF]

, 2013
In this paper we consider a modified version of the classical optimal dividends problem of de Finetti in which the dividend payments subject to a penalty at ruin.
C. Yin, Yuzhen Wen
semanticscholar   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Historical and logical analysis of research on the development of profes-sional value orientations of students in the context of Internet socialization

Вестник Тамбовского университета. Серия: Гуманитарные науки, 2020
We examine the formation of the concept of “value orientations”, “professional value orientations of students”. The classification is presented taking into account the following professional value orientations: “professional and personal”, “professional ...
M. S. Chvanova, I. A. Kiselyova
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Analisis Jaringan 4G untuk Aplikasi Smart Ambulance

Emitor: Jurnal Teknik Elektro
Intelligent Transport System (ITS) is an intelligent traffic system used for traffic management and engineering. The ITS network uses inter-vehicle telecommunication technology. The city of Semarang is one of the cities that will establish ITS technology.
Ari Endang Jayati, Harmini, Diah Setyati Budiningrum   +2 more
doaj   +1 more source

Terminal conditions as efficent instruments for numerical detection of the saddlepoint paths: a linear algebra non-robustness argument. [PDF]

In this paper, we address a criticism against the usual prescriptions on the introduction of terminal conditions as the principal numerical instruments for detecting the saddlepoint solutions of consistent expectations models. The argumentation is purely
Boucekkine, Raouf
core  

Backward Stochatic Differential Equations II [PDF]

, 2005
In a preceding article, we have studied a generalization of the problem of finding a martingale on a manifold whose terminal value is known. This article completes the results obtained in the first article by providing uniqueness and existence theorems ...
Blache, Fabrice
core   +2 more sources