Results 51 to 60 of about 842,336 (266)
Results in Control and OptimizationRobot control using reinforcement learning has become popular, but its learning process often terminates midway through an episode for safety and time-saving reasons.
Taisuke Kobayashi
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A Compound Controller Design for a Buck Converter
Energies, 2018 In order to improve the performance of the closed-loop Buck converter control system, a compound control scheme based on nonlinear disturbance observer (DO) and nonsingular terminal sliding mode (TSM) was developed to control the Buck converter.
Yueping Sun +3 more
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
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KAJIAN TENTANG AKTIVITAS PENGELOLAAN RETRIBUSI TERMINAL DI KOTA MALANG
Jurnal Ekonomi Modernisasi, 2012 Tujuan penelitian ini adalah: (1) untuk menguji dan menjelaskan variabel-variabel: perencanaan, kompetensi aparatur, sarana dan prasarana kerja, pengawasan, dan koordinasi secara parsial dan simultan berpengaruh terhadap efektivitas pengelolaan ...
Abdul Halim
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Electronic Journal of Differential Equations, 2019 In this work, we construct new definitions for a causal terminal value problem involving Riemann-Liouville fractional derivatives, and study the unique solution by combining techniques from generalized quasilinearization.
Coskun Yakar, Mehmet Arslan
doaj
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source