Results 21 to 30 of about 13,451 (179)

EVALUATION OF INTRAPLACENTAL VILLOUS MICROVASCULAR DENSITY AND VASCULAR SURFACE AREA IN PREGNANCY INDUCED HYPERTENSION AND ITS CORRELATION TO NEWBORN BODY WEIGHT

The Iraqi Journal of Medical Sciences, 2016
Background: Preeclampsia is a major problem in obstetric practice; it is considered one of the largest causes of maternal and perinatal morbidity and mortality, and one of the most important causes of intrauterine growth restriction and low birth weight.
Huda R.K. Kamona, Zainab H.H. Al-Amily, Sarmad I. Al-Marsoummi   +2 more
doaj   +6 more sources

MORPHOFUNCTIONAL FEATURES OF THE PLACENTA IN PREGNANT WOMEN WITH TUBERCULOSIS

Паёми Сино, 2023
Objective: To study the morphology of the placenta in pregnant women with TB Methods: The morphology of the 26 placentas was evaluated in this study, out of which 15 were from women with various forms and localizations of TB (main group), while 11 ...
S.SH. VALDOSHOVA
doaj   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Charting Endocrine Progenitors Across Species and Organs

Advanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing, Michael Sterr, Özüm Sehnaz Caliskan, Lama Saber, Nicole Katarina Rogers, Samuel Ogden, Kei Kozawa, Christos Karampelias, Jessica Jaki, Aimée Bastidas‐Ponce, Falk Janos Farkas, Oliver Czarnecki, Osvaldo Rodrigues Pereira, Perla Cota, Valerie Vandenbempt, Diego Balboa, Anika Böttcher, Natalie Krahmer, Mohammad Lotfollahi, Julie B. Sneddon, Heiko Lickert, Mostafa Bakhti   +21 more
wiley   +1 more source

HISTOMORPHOMETRIC AND ENDOTHELIN-1 IMMUNOHISTOCHEMICAL STUDY OF HUMAN PLACENTAL VILLI CORRELATED WITH UMBILICAL CORD COILING INDEX

The Iraqi Journal of Medical Sciences, 2017
Background: Umbilical cord coiling index plays a role in predicting the pregnancy outcome and risk of low birth weight. Endothelin-1 binding sites exist on placental stem villi vessels and trophoblastic layer of the villi.
Hayder J. Mubarak, Sarah A. Ahmed
doaj   +6 more sources

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source

Histologic changes of the placenta in chronic subcompensated placental insufficiency in women with COVID-19 of moderate severity in the second and third trimesters of pregnancy

Якутский медицинский журнал
The histologic study of placental tissues in women with subcompensated chronic placental insufficiency associated with moderate COVID-19 was conducted.
I. A. Andrievskaya, T. S. Churikova, O. L. Kutepova   +2 more
doaj   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

PATHOMORPHOLOGICAL CHANGES OF THE PLACENTA IN CORONAVIRUS DISEASE (COVID-19) IN PREGNANT WOMEN AT 19-32 WEEKS OF GESTATION

Proceedings of the Shevchenko Scientific Society: Medical Sciences
Introduction. The morphology of the placenta (chorion) changes during pregnancy. Immature intermediate villi formed during the first two trimesters are developmental steps towards the stem villi. A cotyledon is the branching of a single stem villus into
Tetiana Savchuk
doaj   +1 more source