Results 101 to 110 of about 658,465 (305)
Fixed to VoIP Interconnection: Regulation with Asymmetric Termination Costs [PDF]
Typically, incumbent providers enjoy a demand-side advantage over any entrant. However, market entrants may enjoy a supply-side advantage in costs over the incumbent, since they are more efficient or operate on innovative technologies, such as the voice ...
Stühmeier, Torben
core
Decoding accuracy in eRF1 mutants and its correlation with pleiotropic quantitative traits in yeast [PDF]
, 2010 Translation termination in eukaryotes typically requires the decoding of one of three stop codons UAA, UAG or UGA by the eukaryotic release factor eRF1.
Mugnier, Pierre M. +11 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On-Net/Off-Net Price Discrimination and 'Bill-and-Keep' vs. 'Cost-Based' Regulation of Mobile Termination Rates [PDF]
This paper surveys the recent literature on competition between mobile network operators in the presence of call externalities and network effects. It shows that the regulation of mobile termination rates based on “long-run incremental costs” increases ...
Pagnozzi, Marco, Harbord, David
core
, 2013 In the original failure-divergence semantic model for Communicating Sequential Processes (CSP) the incomplete treatment of successful process termination, and in particular parallel termination, permitted unnatural processes to be defined where the ...
d'Inverno, M. +3 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Termination of Pregnancy Prescribed Informaiton Reporting Form
, 2017 To comply with the Northern Territory Termination of Pregnancy Law Reform Regulations the following information must be provided within the following timeframes: i. Early medical termination ? within 28 days of the last consultation with the woman ii.
Women's Health Strategy
core
Terminal Lucidity: Envisioning the Future of the Terminal
2025 IEEE/ACM 33rd International Conference on Program Comprehension (ICPC)The Unix terminal, or just simply, the terminal, can be found being applied in almost every facet of computing. It is available across all major platforms and often integrated into other applications. Due to its ubiquity, even marginal improvements to the terminal have the potential to make massive improvements to productivity on a global scale.
Michael MacInnis +2 more
openaire +2 more sources