Results 81 to 90 of about 479,379 (269)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Terminal care. Home terminal care.

Nihon Naika Gakkai Zasshi, 1996
在宅ターミナルケアは家族の負担はあるものの患者にとっては贅沢な医療である.現在の日本で在宅医療を行うには,まだまだ多くの問題がある.しかしながら,患者,家族がそれを望む以上,医療者も行政もそれに応えるシステムをつくる時期にきていることも事実である.在宅ターミナルケアでは患者のみならず家族の身体的・精神的ケア,インフォームドコンセント,また臨死期の対応など多くの課題を抱えている.本稿ではそれらについて考察した.
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Demonstrating the utility of a drought termination framework: prospects for groundwater level recovery in England and Wales in 2018 or beyond

Environmental Research Letters, 2018
During prolonged droughts, information is needed about when and how the extreme event is likely to terminate. A drought termination framework based on historical data comprising current rate and historical ensemble approaches is presented here for ...
Simon Parry, Rob Wilby, Christel Prudhomme, Paul Wood, Andrew McKenzie   +4 more
doaj   +1 more source

Terminated [PDF]

Journal of Thrombosis and Haemostasis, 2014
F R, Rosendaal, P H, Reitsma
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Penghentian Praktik Qard Beragun Emas Berdasarkan Surat Edaran Bank Indonesia Nomor 14/7/DPBS Tahun 2012 Pada Perbankan Syariah

Kanun, 2018
Berdasarkan Peraturan Bank Indonesia Nomor: 7/46/PBI/2005 tentang Akad Penghimpunan dan Penyaluran Dana Bagi Bank yang Melaksanakan Kegiatan Usaha berdasarkan Prinsip Syariah menyebutkan “Qard adalah suatu akad penyaluran dana oleh Bank Syariah atau Unit
Humaira Humaira
doaj   +1 more source

Proof Pearl: The Termination Analysis of Terminator [PDF]

, 2007
TERMINATOR is a static analysis tool developed by Microsoft Research for proving termination of Windows device drivers written in C. This proof pearl describes a formalization in higher order logic of the program analysis employed by Terminator, and verifies that if the analysis succeeds then program termination logically follows.
openaire   +1 more source

Terminal Myelocystocele [PDF]

Neurosurgery, 2013
no ...
openaire   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source