Results 41 to 50 of about 113,738 (266)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

TERNARY ∗-BANDS ARE GLOBALLY DETERMINED

open access: yesUral Mathematical Journal, 2023
A non-empty set \(S\) together with the ternary operation denoted by juxtaposition is said to be ternary semigroup if it satisfies the associativity property \(ab(cde)=a(bcd)e=(abc)de\) for all \(a,b,c,d,e\in S\).
Indrani Dutta, Sukhendu Kar
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Classification of Monogenic Ternary Semigroups [PDF]

open access: yesMathematics Interdisciplinary Research, 2018
The aim of this paper is to classify all monogenic ternary semigroups, up to isomorphism. We divide them to two groups: finite and infinite. We show that every infinite monogenic ternary semigroup is isomorphic to the ternary semigroup O, the odd ...
Nahid Ashrafi, Zahra Yazdanmehr
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Efficiency of cement-admixture systems in mortars with binary and ternary Portland cements

open access: yesDyna, 2018
Compared to conventional concrete, high-performance concrete production offers such benefits as greater ease of placement, smaller sections, improved finishing and higher strength and durability.
María Eva Sosa   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

On the Ternary Relation and Conditionality

open access: yesJournal of Philosophical Logic, 2011
The authors of this paper provide three philosophical explanations of Routley and Meyer's ternary relational semantics for relevant logics regarding the concept of conditionality. They consider three ways of understanding conditionality (those that can be found in the frameworks of modal, intuitionistic and conditional logics) and show that the Routley-
J. C. Beall   +10 more
openaire   +3 more sources

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